Dual-pathway STING activation and chemodynamic therapy for improved anti-tumor therapy

W Xu, L Qiao, Z Wang, Y Qian, L Li, Q Sun… - Chemical Engineering …, 2023 - Elsevier
The cyclic-GMP-AMP synthetase stimulator of interferon genes (cGAS-STING) pathway is a
naturally occurring immune pathway activated by cytosolic DNA. The end products of this …

Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives.

TA Farghaly, KM Dawood - Mini Reviews in Medicinal Chemistry, 2022 - europepmc.org
Despite several reports and reviews addressing the biological significance of pyrazoles and
oxazines, no comprehensive work on the pyrazolo oxazine fused ring system has been …