The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Urinary tract infections (UTIs) represent one of the most common infections that are
frequently encountered in health care facilities. One of the main mechanisms used by …

The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

The increasing resistance of pathogen fungi poses a global public concern. There are
several limitations in current antifungals, including few available fungicides, severe toxicity …

Candida infections (candidiasis) are the most prevalent opportunistic fungal infection on
humans and, as such, a major public health problem. In recent decades, candidiasis has …

The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …