Globally the incidence of hepatocellular carcinoma (HCC) is on an upsurge. Evidence is
accumulating that liver disorders like nonalcoholic fatty liver disease (NAFLD) and its more …

Background Diabetic nephropathy and hepatopathy are health problems described by
specific renal and hepatic structure and function disturbances. The protective effects of the …

Apelin receptor (APJ) ligands elabela (ELA) and apelin have divergent distributions and
function differently in vitro and in vivo. Whether differences exist in their capacity of …

Skeletal disorder is of concern to the poultry industry as it affects animal welfare and
production performance. Traditional Chinese medicine could improve bone quality and …

Fine‐tuning of G protein‐coupled receptor (GPCR) signaling is important to maintain cellular
homeostasis. Recent studies demonstrated that lateral GPCR interactions in the cell …

Context: Fetal growth restriction increases adverse pregnancy outcomes such as preterm
birth and intrauterine fetal death. Apelin is a secreted peptide expressed in placental …

This study was designed to investigate the effectiveness of protamine sulfate as an apelin
receptor blocker on cholestatic liver fibrosis persuaded by common bile duct ligation (BDL) …

L'apéline, un peptide d'origine neuro-endocrine, et son récepteur (Apéline-R) sont co-
localisés avec l'arginine-vasopressine (AVP) dans les neurones magnocellulaires …

Objective: Research in recent years focused on the role of the apelin-APJ axis in pathologic
fibrosis. The axis includes the parenchyma and mesenchymal cells of most organs …