Epidemiology and management of uterine fibroids

E Giuliani, S As‐Sanie, EE Marsh - International Journal of …, 2020 - Wiley Online Library
Uterine leiomyomas are one of the most common and yet understudied diseases in women.
These tumors, commonly known as fibroids, affect women mainly during their reproductive …

Molecular and cellular insights into the development of uterine fibroids

A Machado-Lopez, C Simón, A Mas - International journal of molecular …, 2021 - mdpi.com
Uterine leiomyomas represent the most common benign gynecologic tumor. These hormone-
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …

Evaluation and management of abnormal uterine bleeding

ML Marnach, SK Laughlin-Tommaso - Mayo Clinic Proceedings, 2019 - Elsevier
Abnormal uterine bleeding (AUB) is a common condition that leads to increased health care
costs and decreased quality of life. A systematic approach to AUB evaluation can simplify …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health
worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy …

Uterine fibroids: an update on current and emerging medical treatment options

M Farris, C Bastianelli, E Rosato, I Brosens… - … and clinical risk …, 2019 - Taylor & Francis
Uterine fibroids are the most common gynecological disorder, classically requiring surgery
when symptomatic. Although attempts at finding a nonsurgical cure date back to centuries, it …

Role of transforming growth factor β in uterine fibroid biology

M Ciebiera, M Włodarczyk, M Wrzosek… - International Journal of …, 2017 - mdpi.com
Uterine fibroids (UFs) are benign tumors of the female genital tract made of the smooth
muscle of the uterus. UF growth depends mostly on the influence of the steroid hormones …

The role of tumor necrosis factor α in the biology of uterine fibroids and the related symptoms

M Ciebiera, M Włodarczyk, M Zgliczyńska… - International journal of …, 2018 - mdpi.com
Uterine fibroids (UFs) are the most common benign tumors of the female genital tract. The
incidence of UFs has been estimated at 25–80% depending on selected population. The …

The evolving role of natural compounds in the medical treatment of uterine fibroids

M Ciebiera, M Ali, L Prince, T Jackson-Bey… - Journal of clinical …, 2020 - mdpi.com
Uterine fibroids (UFs) remain a significant health issue for many women, with a
disproportionate impact on women of color, likely due to both genetic and environmental …

Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women

M Ali, S AR, A Al Hendy - Expert review of clinical pharmacology, 2021 - Taylor & Francis
ABSTRACT Introduction Uterine fibroids (UFs) are the most common benign tumor arising
from myometrium of reproductive age women, with significant financial burden estimated in …

Reversible interventions for menstrual management in adolescents and young adults with gender incongruence

RC Roden - Therapeutic Advances in Reproductive Health, 2023 - journals.sagepub.com
The newly released World Professional Association for Transgender Health Standards of
Care, 8th Edition specify that adolescents should be offered menstrual suppression as part …