Clinical practice shows that when single-target drugs treat multi-factor diseases such as
tumors, cardiovascular system and endocrine system diseases, it is often difficult to achieve …

Owing to the unique DNA damaging cytotoxicity, platinum (Pt)-based chemotherapy has
long been the first-line choice for clinical oncology. Unfortunately, Pt drugs are restricted by …

Clinical evidence supports a role for the extracellular matrix (ECM) in cancer plasticity
across multiple tumor types. The lack of in vitro models that represent the native ECMs is a …

Aims To investigate the collateral sensitivity (CS) of ABCB1-positive multidrug resistant
(MDR) colorectal cancer cells to the survivin inhibitor MX106–4C and the mechanism …

A wound occurs when the epidermis and dermis of the skin are damaged internally and
externally. The traditional wound healing method is unsatisfactory, which will prolong the …

Over the past decade, researchers have proposed a new class of drug delivery systems, bio-
hybrid micro-robots, designed with a variety of living cell-driven micro-robots that utilize the …

Hydrogels have outstanding research and application prospects in the field of product
design. Among them, the design and preparation of cellulose-based functional hydrogels …

As a member of PHB (prohibitin1) family, PHB plays important roles in many cancers, but its
property in bladder carcinoma aggressiveness is unknown. This research was to explore the …

Reprogramming of energy metabolism is one of the basic characteristics of cancer and has
been proved to be an important cancer treatment strategy. Isocitrate dehydrogenases (IDHs) …

Elephantopus scaber, globally acknowledged for its edible and medicinal uses, remains
underexplored despite the identification of active compounds. This research explores …