Though totipotency and pluripotency are transient during early embryogenesis, they
establish the foundation for the development of all mammals. Studying these in vivo has …

In vitro stem cell models that replicate human gastrulation have been generated, but they
lack the essential extraembryonic cells needed for embryonic development, morphogenesis …

Developing functional organs from stem cells remains a challenging goal in regenerative
medicine. Existing methodologies, such as tissue engineering, bioprinting, and organoids …

Understanding the mechanisms of blastocyst formation and implantation is critical for
improving farm animal reproduction but is hampered by a limited supply of embryos. Here …

Here, we report that a chemical cocktail (LCDM: leukemia inhibitory factor [LIF], CHIR99021,
dimethinedene maleate [DiM], minocycline hydrochloride), previously developed for …

Liver fibrosis can cause hepatitis B virus (HBV)‐associated hepatocellular carcinoma.
Menstrual blood‐derived mesenchymal stem cells (MenSCs) can ameliorate liver fibrosis …

Despite advances in stem cell cultures, modeling early human development with stem cells
in a dish remains challenging. Research by Hislop et al., 1 Okubo et al., 2 and Wei et al. 3 …

Unraveling the function of FGF signaling in human hypoblast specialization - ScienceDirect
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Our study concentrated on the expression of miRNA-375 in the hypothalamic-pituitary-
gonadal axis of female Hu sheep. The investigation involved cloning the precursor …

Trophoblast stem cells (TSCs) are a proliferative multipotent population derived from the
trophectoderm of the blastocyst, which will give rise to all the functional cell types of the …