[HTML][HTML] Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …
molecular-weight bioactive agents have also been used for a variety of other medicinal …
Mobile genetic elements associated with antimicrobial resistance
SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …
increasing major health care problem around the world. It is now abundantly clear that both …
Sequencing-based methods and resources to study antimicrobial resistance
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures
PS Krawczyk, L Lipinski… - Nucleic acids research, 2018 - academic.oup.com
Plasmids are mobile genetics elements that play an important role in the environmental
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …
plasmidSPAdes: assembling plasmids from whole genome sequencing data
Motivation: Plasmids are stably maintained extra-chromosomal genetic elements that
replicate independently from the host cell's chromosomes. Although plasmids harbor …
replicate independently from the host cell's chromosomes. Although plasmids harbor …
Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review
K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …
priority pathogens owing to their high association with mortalities and morbidities …
On the (im) possibility of reconstructing plasmids from whole-genome short-read sequencing data
S Arredondo-Alonso, RJ Willems… - Microbial …, 2017 - microbiologyresearch.org
To benchmark algorithms for automated plasmid sequence reconstruction from short-read
sequencing data, we selected 42 publicly available complete bacterial genome sequences …
sequencing data, we selected 42 publicly available complete bacterial genome sequences …
Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC
The recent widespread emergence of carbapenem resistance in Enterobacteriaceae is a
major public health concern, as carbapenems are a therapy of last resort against this family …
major public health concern, as carbapenems are a therapy of last resort against this family …
[HTML][HTML] The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee
MJ Ellington, O Ekelund, FM Aarestrup… - Clinical microbiology …, 2017 - Elsevier
Whole genome sequencing (WGS) offers the potential to predict antimicrobial susceptibility
from a single assay. The European Committee on Antimicrobial Susceptibility Testing …
from a single assay. The European Committee on Antimicrobial Susceptibility Testing …