The production of melanin significantly enhances the virulence of many important human
pathogenic fungi. Despite fungal melanin's importance in human disease, as well as …

Melanins are enigmatic pigments that are produced by a wide variety of microorganisms
including several species of pathogenic bacteria, fungi and helminthes. The study of …

Melanins represent virulence factors for several pathogenic fungi; the number of examples is
growing. Thus, albino mutants of several genera (in one case, mutated precisely in the …

The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

The interaction between fungal pathogens with the host frequently results in morphological
changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus …

Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

Cryptococcus neoformans strains classically have been grouped into two varieties that
included five serotypes known as C. neoformans variety neoformans (serotypes A, D, and …

Melanin synthesis has been associated with virulence for the human pathogenic fungus
Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize …

Melanin has been referred to as 'fungal armor'due to the ability of the polymer to protect
microorganisms against a broad range of toxic insults. Recent publications continue to …

Cryptococcus neoformans is an opportunistic fungal pathogen that infects the human central
nervous system. This pathogen elaborates two specialized virulence factors: the antioxidant …