Natural metalloproteins perform many functions—ranging from sensing to electron transfer
and catalysis—in which the position and property of each ligand and metal are dictated by …

Protein design is a valuable tool for understanding the fundamental factors that dictate
protein structure and function. The field of protein design has seen significant progress over …

Through their unique and specific interactions with various metal ions, naturally occurring
proteins control structures and functions of many biological processes and functions in …

The construction of complex protein folds relies on the precise conversion of a linear
polypeptide chain into a compact 3-dimensional structure. The interplay of forces that link …

The coiled coil is a superhelical protein structural motif that consists of two or more α-helical
peptides that are wrapped around each other in superhelical fashion. Coiled coils are …

Given the well-defined enzymology of the manganese catalases and recent advances in the
structural biology of these proteins, this is an excellent area for corroborative modeling of the …

Hemes remain one of the most visible and versatile classes of cofactors utilized in biology. 1
Since their discovery, the structural and functional aspects of heme proteins have fascinated …

Zinc is an essential element required for the function of more than 300 enzymes spanning all
classes. Despite years of dedicated study, questions regarding the connections between …

Stimuli‐responsive peptides and proteins are an exciting class of smart biomaterials for
various applications and have received significant attention over the past decades. A wide …

Dehydrins are hydrophilic proteins that are responsive to osmotic stress, such as drought,
cold, and salinity in plants. Although they have been hypothesized to stabilize …