De novo metalloprotein design
Natural metalloproteins perform many functions—ranging from sensing to electron transfer
and catalysis—in which the position and property of each ligand and metal are dictated by …
and catalysis—in which the position and property of each ligand and metal are dictated by …
Protein design: toward functional metalloenzymes
F Yu, VM Cangelosi, ML Zastrow, M Tegoni… - Chemical …, 2014 - ACS Publications
Protein design is a valuable tool for understanding the fundamental factors that dictate
protein structure and function. The field of protein design has seen significant progress over …
protein structure and function. The field of protein design has seen significant progress over …
Peptide self-assembly triggered by metal ions
Through their unique and specific interactions with various metal ions, naturally occurring
proteins control structures and functions of many biological processes and functions in …
proteins control structures and functions of many biological processes and functions in …
Design of folded peptides
J Venkatraman, SC Shankaramma… - Chemical reviews, 2001 - ACS Publications
The construction of complex protein folds relies on the precise conversion of a linear
polypeptide chain into a compact 3-dimensional structure. The interplay of forces that link …
polypeptide chain into a compact 3-dimensional structure. The interplay of forces that link …
Coiled coils: attractive protein folding motifs for the fabrication of self-assembled, responsive and bioactive materials
The coiled coil is a superhelical protein structural motif that consists of two or more α-helical
peptides that are wrapped around each other in superhelical fashion. Coiled coils are …
peptides that are wrapped around each other in superhelical fashion. Coiled coils are …
Structural, spectroscopic, and reactivity models for the manganese catalases
AJ Wu, JE Penner-Hahn, VL Pecoraro - Chemical Reviews, 2004 - ACS Publications
Given the well-defined enzymology of the manganese catalases and recent advances in the
structural biology of these proteins, this is an excellent area for corroborative modeling of the …
structural biology of these proteins, this is an excellent area for corroborative modeling of the …
Heme protein assemblies
CJ Reedy, BR Gibney - Chemical reviews, 2004 - ACS Publications
Hemes remain one of the most visible and versatile classes of cofactors utilized in biology. 1
Since their discovery, the structural and functional aspects of heme proteins have fascinated …
Since their discovery, the structural and functional aspects of heme proteins have fascinated …
Designing hydrolytic zinc metalloenzymes
ML Zastrow, VL Pecoraro - Biochemistry, 2014 - ACS Publications
Zinc is an essential element required for the function of more than 300 enzymes spanning all
classes. Despite years of dedicated study, questions regarding the connections between …
classes. Despite years of dedicated study, questions regarding the connections between …
Design of Stimuli‐Responsive Peptides and Proteins
Stimuli‐responsive peptides and proteins are an exciting class of smart biomaterials for
various applications and have received significant attention over the past decades. A wide …
various applications and have received significant attention over the past decades. A wide …
Metal binding by citrus dehydrin with histidine-rich domains
M Hara, M Fujinaga, T Kuboi - Journal of experimental botany, 2005 - academic.oup.com
Dehydrins are hydrophilic proteins that are responsive to osmotic stress, such as drought,
cold, and salinity in plants. Although they have been hypothesized to stabilize …
cold, and salinity in plants. Although they have been hypothesized to stabilize …