In 1994, Ye and McKervey published a paper in Chemical Reviews entitled “Organic
Synthesis with α-Diazocarbonyl Compounds”. 1 Our intention then was to draw attention to …

The activation of a substrate by a chiral catalyst is now regarded as one of the most powerful
strategies that can be employed in the art of asymmetric synthesis. 1 The development of …

Recently, the use of enantiomerically pure counteranions for the induction of asymmetry in
reactions proceeding through cationic intermediates has emerged as an exciting new …

From its earliest observation as an unusual reaction only a half century ago, 1 the insertion
of a carbene into a carbonrhydrogen bond has attracted considerable interest because of its …

The demand for more efficient ways to construct complex chemical structures from simple,
readily available precursors continues unabated. A very attractive way to meet this demand …

Although the first ylide appeared as early as the 1900s, the recognition of these structurally
interesting compounds as synthetically useful reagents was only realized after the birth of …

Chiral phosphoric acids derived from axially chiral biaryls and related chiral Brønsted acids
have emerged as an attractive and widely applicable class of enantioselective …

The history of the β-lactam (2-azetidinone) ring, arguably one of the most acclaimed
heterocycles studied over the last century, tells a tale rich in curiosity, serendipity, and …

Achirale Dirhodium (II)‐Carboxylate und spirocyclische chirale Phosphorsäuren (SPA)
kooperieren in hoch enantioselektiven N‐H‐Insertionen, die hohe Ausbeuten liefern und …

Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …