APT‐weighted MRI: techniques, current neuro applications, and challenging issues

J Zhou, HY Heo, L Knutsson… - Journal of Magnetic …, 2019 - Wiley Online Library
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …

Arterial spin labeling perfusion of the brain: emerging clinical applications

S Haller, G Zaharchuk, DL Thomas, KO Lovblad… - Radiology, 2016 - pubs.rsna.org
Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …

Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome

JPB O'Connor, CJ Rose, JC Waterton… - Clinical Cancer …, 2015 - AACR
Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance
and may influence response to therapy. Imaging can quantify the spatial variation in …

Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging

M Law, S Yang, H Wang, JS Babb… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Sensitivity, positive predictive value (PPV), and negative
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high …

Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not

JL Boxerman, KM Schmainda… - American Journal of …, 2006 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) estimates for high-
grade gliomas computed with dynamic susceptibility contrast MR imaging are artificially …

Rare-earth based materials: an effective toolbox for brain imaging, therapy, monitoring and neuromodulation

Z Wei, Y Liu, B Li, J Li, S Lu, X Xing, K Liu… - Light: Science & …, 2022 - nature.com
Brain diseases, including tumors and neurodegenerative disorders, are among the most
serious health problems. Non-invasively high-resolution imaging methods are required to …

Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous …

JS Weinstein, CG Varallyay, E Dosa… - Journal of Cerebral …, 2010 - journals.sagepub.com
Superparamagnetic iron oxide nanoparticles have diverse diagnostic and potential
therapeutic applications in the central nervous system (CNS). They are useful as magnetic …

Modern brain tumor imaging

MC Mabray, RF Barajas, S Cha - Brain tumor research and …, 2015 - synapse.koreamed.org
The imaging and clinical management of patients with brain tumor continue to evolve over
time and now heavily rely on physiologic imaging in addition to high-resolution structural …

Gliomas: Histogram Analysis of Apparent Diffusion Coefficient Maps with Standard- or High-b-Value Diffusion-weighted MR Imaging—Correlation with Tumor Grade

Y Kang, SH Choi, YJ Kim, KG Kim, CH Sohn, JH Kim… - Radiology, 2011 - pubs.rsna.org
Purpose To explore the role of histogram analysis of apparent diffusion coefficient (ADC)
maps based on entire tumor volume data in determining glioma grade and to evaluate the …

Update on brain tumor imaging: from anatomy to physiology

S Cha - American Journal of Neuroradiology, 2006 - Am Soc Neuroradiology
The role of neuroimaging in patients with brain tumors is no longer simply to evaluate
structural abnormality and identify tumor-related complications. By transitioning from a …