Chemical Biology of H2S Signaling through Persulfidation
MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
Drug delivery by supramolecular design
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …
important role in many physiological processes and joining nitric oxide and carbon …
International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
Peptide–drug conjugates as effective prodrug strategies for targeted delivery
Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …
combine one or more drug molecules with a short peptide through a biodegradable linker …
Self-assembling prodrugs
AG Cheetham, RW Chakroun, W Ma… - Chemical Society Reviews, 2017 - pubs.rsc.org
Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …
A practical guide to working with H 2 S at the interface of chemistry and biology
Hydrogen sulfide (H2S) is the most recently accepted endogenously produced
gasotransmitter and is now implicated in a variety of physiological functions. In this tutorial …
gasotransmitter and is now implicated in a variety of physiological functions. In this tutorial …
Self-assembly, bioactivity, and nanomaterials applications of peptide conjugates with bulky aromatic terminal groups
IW Hamley - ACS Applied Bio Materials, 2023 - ACS Publications
The self-assembly and structural and functional properties of peptide conjugates containing
bulky terminal aromatic substituents are reviewed with a particular focus on bioactivity …
bulky terminal aromatic substituents are reviewed with a particular focus on bioactivity …
Progress and perspective on hydrogen sulfide donors and their biomedical applications
ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …
Hydrogen sulfide: an emerging precision strategy for gas therapy
H Ding, J Chang, F He, S Gai… - Advanced Healthcare …, 2022 - Wiley Online Library
Advances in nanotechnology have enabled the rapid development of stimuli‐responsive
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …