GnRH and GnRH receptors in the pathophysiology of the human female reproductive system

R Maggi, AM Cariboni, MM Marelli… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Human reproduction depends on an intact hypothalamic–pituitary–gonadal
(HPG) axis. Hypothalamic gonadotrophin-releasing hormone (GnRH) has been recognized …

The neuroendocrine timing of puberty

FJP Ebling - Reproduction, 2005 - rep.bioscientifica.com
Puberty is the attainment of fertility, a process encompassing morphological, physiological
and behavioural development. The increased hypothalamic secretion of the gonadotrophin …

Development of the neurons controlling fertility in humans: new insights from 3D imaging and transparent fetal brains

F Casoni, SA Malone, M Belle, F Luzzati… - …, 2016 - journals.biologists.com
Fertility in mammals is controlled by hypothalamic neurons that secrete gonadotropin-
releasing hormone (GnRH). These neurons differentiate in the olfactory placodes during …

Social regulation of gonadotropin-releasing hormone

SA White, T Nguyen… - Journal of Experimental …, 2002 - journals.biologists.com
Behavioral interactions among social animals can regulate both reproductive behavior and
fertility. A prime example of socially regulated reproduction occurs in the cichlid fish …

Evolutionary development of three gonadotropin-releasing hormone (GnRH) systems in vertebrates

EA Dubois, MA Zandbergen, J Peute, HJG Th - Brain Research Bulletin, 2002 - Elsevier
Gonadotropin-releasing hormone (GnRH) is the neuropeptide that links the brain to the
reproductive system. Most vertebrate species express two forms of GnRH, which differ in …

[图书][B] GnRH: the master molecule of reproduction

AC Gore - 2002 - books.google.com
Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive
function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of …

The ovarian cycle

JAS Richards - Vitamins and hormones, 2018 - Elsevier
The “ovarian cycle” is an exquisite and dynamic endocrine system that includes ovarian
events, hypothalamic–pituitary interactions, uterine endometrial and myometrial changes …

Diversity of actions of GnRHs mediated by ligand-induced selective signaling

RP Millar, AJ Pawson, K Morgan, EF Rissman… - Frontiers in …, 2008 - Elsevier
Geoffrey Wingfield Harris' demonstration of hypothalamic hormones regulating pituitary
function led to their structural identification and therapeutic utilization in a wide spectrum of …

Synthesis and secretion of GnRH

IJ Clarke, S Pompolo - Animal reproduction science, 2005 - Elsevier
Comprehensive studies have provided a clear understanding of the effects of gonadal
steroids on the secretion of gonadotropin releasing hormone (GnRH), but some inconsistent …

Pituitary gonadotropin-releasing hormone (GnRH) receptor: structure, distribution and regulation of expression

LA Rispoli, TM Nett - Animal reproduction science, 2005 - Elsevier
Reproduction in mammals is controlled by interactions between the hypothalamus, anterior
pituitary and gonads. Interaction of GnRH with its cognate receptor is essential to regulating …