Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: a systematic review and meta-analysis of …
We examined the efficacy and acceptability of non-invasive brain stimulation in adult
unipolar and bipolar depression. Randomised sham-controlled trials of transcranial direct …
unipolar and bipolar depression. Randomised sham-controlled trials of transcranial direct …
Defining the vulnerable patient with myeloma—a frailty position paper of the European Myeloma Network
G Cook, A Larocca, T Facon, S Zweegman… - Leukemia, 2020 - nature.com
As the treatment landscape continues to evolve towards the application of precision
medicine in multiple myeloma (MM), there is a clear need to identify those patients who are …
medicine in multiple myeloma (MM), there is a clear need to identify those patients who are …
Four simple ways to increase power without increasing the sample size
SE Lazic - Laboratory animals, 2018 - journals.sagepub.com
Underpowered experiments have three problems: true effects are harder to detect, the true
effects that are detected tend to have inflated effect sizes and as power decreases so does …
effects that are detected tend to have inflated effect sizes and as power decreases so does …
[图书][B] Experimental design for laboratory biologists
SE Lazic - 2016 - books.google.com
Specifically intended for lab-based biomedical researchers, this practical guide shows how
to design experiments that are reproducible, with low bias, high precision, and widely …
to design experiments that are reproducible, with low bias, high precision, and widely …
Spurious interaction as a result of categorization
M Thoresen - BMC medical research methodology, 2019 - Springer
Background It is common in applied epidemiological and clinical research to convert
continuous variables into categorical variables by grouping values into categories. Such …
continuous variables into categorical variables by grouping values into categories. Such …
Variations in hippocampal white matter diffusivity differentiate response to electroconvulsive therapy in major depression
Background Electroconvulsive therapy (ECT) is an effective treatment for severe depression
and is shown to increase hippocampal volume and modulate hippocampal functional …
and is shown to increase hippocampal volume and modulate hippocampal functional …
A novel approach to determine two optimal cut-points of a continuous predictor with a U-shaped relationship to hazard ratio in survival data: simulation and application
Background In clinical and epidemiological researches, continuous predictors are often
discretized into categorical variables for classification of patients. When the relationship …
discretized into categorical variables for classification of patients. When the relationship …
Patient reported outcome measures in clinical trials should be initially analyzed as continuous outcomes for statistical significance and responder analyses should be …
Objective To evaluate the power of responder analyses in a randomized controlled trial.
Study design and setting Simulations were based on the Chronic Kidney Disease …
Study design and setting Simulations were based on the Chronic Kidney Disease …
The risks of biomarker-based epidemiology: associations of circulating calcium levels with age, mortality, and frailty vary substantially across populations
Recent studies have shown contradictory associations between calcium levels and health
outcomes. We suspected these conflicting results were the consequence of more general …
outcomes. We suspected these conflicting results were the consequence of more general …
Index or illusion: The case of frailty indices in the Health and Retirement Study
Introduction Frailty is a geriatric syndrome that has been defined differently with various
indices. Without a uniform definition, it remains unclear how to interpret and compare …
indices. Without a uniform definition, it remains unclear how to interpret and compare …