Ribosome profiling reveals the what, when, where and how of protein synthesis

GA Brar, JS Weissman - Nature reviews Molecular cell biology, 2015 - nature.com
Ribosome profiling, which involves the deep sequencing of ribosome-protected mRNA
fragments, is a powerful tool for globally monitoring translation in vivo. The method has …

Global signatures of protein and mRNA expression levels

R de Sousa Abreu, LO Penalva, EM Marcotte… - Molecular …, 2009 - pubs.rsc.org
Cellular states are determined by differential expression of the cell's proteins. The
relationship between protein and mRNA expression levels informs about the combined …

Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis

B Jiang, Z Zhong, L Gu, X Zhang, J Wei, C Ye, G Lin… - Nature Plants, 2023 - nature.com
Light regulates chlorophyll homeostasis and photosynthesis via various molecular
mechanisms in plants. The light regulation of transcription and protein stability of nuclear …

[HTML][HTML] Plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection

S Wang, B He, H Wu, Q Cai, O Ramírez-Sánchez… - Cell Host & Microbe, 2024 - cell.com
Cross-kingdom small RNA trafficking between hosts and microbes modulates gene
expression in the interacting partners during infection. However, whether other RNAs are …

Hairy Root Transformation Using Agrobacterium rhizogenes as a Tool for Exploring Cell Type-Specific Gene Expression and Function Using Tomato as a Model

M Ron, K Kajala, G Pauluzzi, D Wang… - Plant …, 2014 - academic.oup.com
Agrobacterium rhizogenes (or Rhizobium rhizogenes) is able to transform plant genomes
and induce the production of hairy roots. We describe the use of A. rhizogenes in tomato …

Translational dynamics revealed by genome-wide profiling of ribosome footprints in Arabidopsis

P Juntawong, T Girke, J Bazin… - Proceedings of the …, 2014 - National Acad Sciences
Translational regulation contributes to plasticity in metabolism and growth that enables
plants to survive in a dynamic environment. Here, we used the precise mapping of ribosome …

[HTML][HTML] A translational profiling approach for the molecular characterization of CNS cell types

M Heiman, A Schaefer, S Gong, JD Peterson, M Day… - Cell, 2008 - cell.com
The cellular heterogeneity of the brain confounds efforts to elucidate the biological
properties of distinct neuronal populations. Using bacterial artificial chromosome (BAC) …

Profiling translatomes of discrete cell populations resolves altered cellular priorities during hypoxia in Arabidopsis

A Mustroph, ME Zanetti, CJH Jang… - Proceedings of the …, 2009 - National Acad Sciences
Multicellular organs are composed of distinct cell types with unique assemblages of
translated mRNAs. Here, ribosome-associated mRNAs were immunopurified from specific …

Global analysis of ribosome-associated noncoding RNAs unveils new modes of translational regulation

J Bazin, K Baerenfaller, SJ Gosai… - Proceedings of the …, 2017 - National Acad Sciences
Eukaryotic transcriptomes contain a major non–protein-coding component that includes
precursors of small RNAs as well as long noncoding RNA (lncRNAs). Here, we utilized the …

Translation regulation in plants: an interesting past, an exciting present and a promising future

C Merchante, AN Stepanova, JM Alonso - The Plant Journal, 2017 - Wiley Online Library
Changes in gene expression are at the core of most biological processes, from cell
differentiation to organ development, including the adaptation of the whole organism to the …