Once a rarely used subset of medical treatments, protein therapeutics have increased
dramatically in number and frequency of use since the introduction of the first recombinant …

Purpose—Our goal is to provide an overview of the current evidence about components of
the evaluation and treatment of adults with acute ischemic stroke. The intended audience is …

Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …

Background The aim of the Safe Implementation of Thrombolysis in Stroke-Monitoring Study
(SITS-MOST) was to assess the safety and efficacy of intravenous alteplase as thrombolytic …

Objectives This article provides recommendations on the use of antithrombotic therapy in
patients with stroke or transient ischemic attack (TIA). Methods We generated treatment …

ContextIntravenous tissue-type plasminogen activator can be beneficial to some patients
when given within 3 hours of stroke onset, but many patients present later after stroke onset …

Purpose—Telestroke is one of the most frequently used and rapidly expanding applications
of telemedicine, delivering much-needed stroke expertise to hospitals and patients. This …

On the old highway maps of America, the main routes were red and the back roads blue.
Now even the colors are changing. But in those brevities just before dawn and a little after …

Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …

ContextRecombinant tissue-type plasminogen activator (rt-PA) improves outcomes for
patients with acute ischemic stroke, but current approved use is limited to within 3 hours of …