Bicyclo [1.1. 0] butanes, as structurally unique compounds with high strained energy and
diverse chemical properties, are becoming increasingly popular building blocks in organic …

Bicyclo [1.1. 0] butanes (BCBs), featuring two fused cyclopropane rings, have found
widespread application in organic synthesis. Their versatile reactivity towards radicals …

Skipped dienes are not only present in fatty acid primary metabolites and natural products
but also serve as reactive intermediates in diverse chemical synthesis. Despite this, the …

This review explores the pivotal role of sulfur in advancing sustainable carbon‐carbon (C−
C) coupling reactions. The unique electronic properties of sulfur, as a soft Lewis base with …

Spirocyclobutane derivatives have gained significant attention in drug discovery programs
due to their broad spectrum of biological activities and clinical applications. Ring-strain in …

A visible-light-induced radical alkylarylation of N-aryl bicyclobutyl amides with α-carbonyl
alkyl bromides for the synthesis of functionalized 3-spirocyclobutyl oxindoles is described in …

An efficient and operationally simple oxidative radical difunctionalization of N-aryl
bicyclobutyl (BCB) amides with aldehydes is described. It was found that acylated 3 …

A palladium-catalyzed allylic amination of vinyl bicyclo [1.1. 0] butanes with amines is
described. This protocol is featured with its novel activation model, broad substrate scope …

In the realm of organic and green chemistry, the functionalization of cyclobutanes presents a
significant challenge, given their unique structural properties and biological relevance …

Abstract Bicyclo [1.1. 0] butanes (BCBs) and [1.1. 1] propellanes (tricyclo [1.1. 1.0 1, 3]
pentanes, TCPs) are structurally unique compounds with different chemical properties …