The development of chiral catalysts that can provide high enantioselectivities across a wide
assortment of substrates or reaction range is a priority for many catalyst design efforts. While …

A catalyst possessing a broad substrate scope, in terms of both turnover and
enantioselectivity, is sometimes called “general”. Despite their great utility in asymmetric …

Organocatalysis has evolved significantly over the last decades, becoming a pillar of
synthetic chemistry, but traditional theoretical approaches based on quantum mechanical …