Gene polymorphisms and circulating levels of MMP-2 and MMP-9: A review of their role in breast cancer risk

SÉÈG Dofara, SL Chang, C Diorio - Anticancer Research, 2020 - ar.iiarjournals.org
MMP-2 and MMP-9 genes have been suggested to play a role in breast cancer. Their
functions have been associated with invasion and metastasis of breast cancer; however …

Genetic epidemiology of breast cancer in Latin America

VA Zavala, SJ Serrano-Gomez, J Dutil, L Fejerman - Genes, 2019 - mdpi.com
The last 10 years witnessed an acceleration of our understanding of what genetic factors
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …

Matrix metalloproteinase gene polymorphisms are associated with breast cancer in the caucasian women of Russia

N Pavlova, S Demin, M Churnosov… - International Journal of …, 2022 - mdpi.com
We conducted this study to explore the association between matrix metalloproteinase (MMP)
gene polymorphisms and breast cancer (BC) risk in the Caucasian women of Russia. In …

Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study

ML Slattery, E John, G Torres-Mejia, M Stern… - PloS one, 2013 - journals.plos.org
Matrix metalloproteinases (MMPs) contribute to cancer through their involvement in cancer
invasion and metastasis. We evaluated genetic variation in MMP1 (9 SNPs), MMP2 (8 …

Meta-analysis of association between matrix metalloproteinases 2, 7 and 9 promoter polymorphisms and cancer risk

B Peng, L Cao, X Ma, W Wang, D Wang, L Yu - Mutagenesis, 2010 - academic.oup.com
Abstract Matrix metalloproteinase (MMP) 2, MMP7 and MMP9 are important members of the
MMP family. Four polymorphisms in the promoter region of these MMPs, which are MMP2 …

Polymorphisms in MMP-1, MMP-2, MMP-7, MMP-13 and MT2A do not contribute to breast, lung and colon cancer risk in polish population

K Białkowska, W Marciniak, M Muszyńska… - Hereditary Cancer in …, 2020 - Springer
Abstract Background Matrix metalloproteinases (MMPs) and metallothioneins (MTs) are Zinc-
related proteins which are involved in processes crucial for carcinogenesis such as …

Genomic disparities in breast cancer among Latinas

F Lynce, KD Graves, L Jandorf, C Ricker… - Cancer …, 2016 - journals.sagepub.com
Background Breast cancer is the most common cancer diagnosed among Latinas in the
United States and the leading cause of cancer-related death among this population. Latinas …

Association of zinc level and polymorphism in MMP-7 gene with prostate cancer in Polish population

K Białkowska, W Marciniak, M Muszyńska, P Baszuk… - PLoS …, 2018 - journals.plos.org
Introduction Prostate cancer is one of the most commonly diagnosed malignancies among
men in Western populations. Evidence reported in the literature suggests that zinc may be …

Higher risk of matrix metalloproteinase (MMP‐2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP‐2) genetic variants to gallbladder cancer

KL Sharma, S Misra, A Kumar, B Mittal - Liver International, 2012 - Wiley Online Library
Background Matrix metalloproteinase belong to family of pericellular collagenases which
degrade extracellular matrix (ECM), and is involved in the modulation and susceptibility of …

Association of promoter polymorphisms in MMP2 and TIMP2 with prostate cancer susceptibility in North India

P Srivastava, TA Lone, R Kapoor, RD Mittal - Archives of medical research, 2012 - Elsevier
BACKGROUND AND AIMS: The importance of matrix metalloproteinases (MMPs) and their
tissue inhibitors (TIMPs) in tumor progression is well documented. MMP2/TIMP2 system has …