A polyurethane-based hydrophilic elastomer with multi-biological functions for small-diameter vascular grafts

S Li, L Yang, Z Zhao, X Yang, H Lv - Acta Biomaterialia, 2024 - Elsevier
Thrombosis and intimal hyperplasia (IH) are two major problems faced by the small-
diameter vascular grafts. Mimicking the native endothelium and physiological elasticity of …

Synthesis and biological evaluation of substituted 4, 6-diarylpyrimidines and 3, 5-diphenyl-4, 5-dihydro-1H-pyrazoles as anti-tubercular agents

V Pathak, HK Maurya, S Sharma, KK Srivastava… - Bioorganic & medicinal …, 2014 - Elsevier
Abstract Various substituted 4, 6-diarylpyrimidin-2-amine (4), 4, 6-diaryl-2-(heteroaryl)
pyrimidine (6) and 1-(3, 5-diaryl-4, 5-dihydro-1H-pyrazol-1-yl) ethanone (7) derivatives were …

The iron-catalyzed construction of 2-aminopyrimidines from alkynenitriles and cyanamides

TK Lane, MH Nguyen, BR D'Souza… - Chemical …, 2013 - pubs.rsc.org
Several cycloaddition catalysts and reagents were surveyed for their effectiveness toward
cyclizing alkynenitriles with cyanamides. Catalytic amounts of FeI2, iPrPDAI and Zn were …

Design, synthesis, molecular docking study and molecular dynamics simulation of new coumarin-pyrimidine hybrid compounds having anticancer and antidiabetic …

DN Toan, ND Thanh, MX Truong, DT Van… - Medicinal Chemistry …, 2023 - Springer
Coumarin-pyrimidine hybrid compounds were synthesized by condensation reaction of α, β-
unsaturated ketones of 6-acetyl-5-hydroxy-4-methylcoumarin with guanidine. The reaction …

Synthesis of Benzo[4,5]imidazo[1,2-c]pyrimidin-1-amines and Their Analogs via Copper-Catalyzed C–N Coupling and Cyclization

PDQ Dao, HK Lee, HS Sohn, NS Yoon, CS Cho - ACS omega, 2017 - ACS Publications
2-(2-Bromovinyl) benzimidazoles and 2-(2-bromophenyl) benzimidazoles react with
cyanamide by microwave irradiation in dimethylformamide in the presence of a catalytic …

[PDF][PDF] Synthesis of novel Naphthalene COX inhibitors for anti-inflammatory activity

AB Pandya, DG Prajapati, SS Pandya - Journal of Applied …, 2012 - japsonline.com
Inflammation forms the part of various diseased conditions. To treat inflammation variety of
anti inflammatory agents are synthesized, they showed undesirable side effects. In order to …

CsOH/γ-Al 2 O 3: A heterogeneous reusable basic catalyst for one-pot synthesis of 2-amino-4, 6-diaryl pyrimidines

A Nimkar, MMV Ramana, R Betkar, P Ranade… - New Journal of …, 2016 - pubs.rsc.org
A new strategy for a one-pot synthesis of 2-amino-4, 6-diaryl pyrimidines using CsOH/γ-
Al2O3 as a heterogeneous, reusable basic catalyst is presented. The developed synthetic …

Design, synthesis and cytotoxicity evaluation of pyrazolyl pyrazoline and pyrazolyl aminopyrimidine derivatives as potential anticancer agents

R Alam, A Alam, AK Panda, Rahisuddin - Medicinal Chemistry Research, 2018 - Springer
In an attempt to find bio-active heterocyclic analogues, a series of novel 1-(5-(3-(aryl)-1-
phenyl-1 H-pyrazol-4-yl)-3-(pyridin-3-yl)-4, 5-dihydropyrazol-1-yl) ethanones 5a–i and 4-(3 …

Synthesis of thioether derivatives of quinazoline-4-one-2-thione and evaluation of their antiplatelet aggregation activity

Z Eskandariyan, M Esfahani Zadeh… - Archives of pharmacal …, 2014 - Springer
Abstract A series of 2-(arylmethylthio)-3-phenylquinazolin-4-one derivatives have been
synthesized and their antiplatelet aggregation activities were assessed against ADP and …

Synthesis and biological evaluation of novel series of aminopyrimidine derivatives as urease inhibitors and antimicrobial agents

LK Adsul, BP Bandgar, HV Chavan… - Journal of enzyme …, 2013 - Taylor & Francis
A novel series of carbazole substituted aminopyrimidines (5a-p) were synthesized and
screened for their in vitro urease inhibition and antimicrobial activity. Among the compounds …