Protein aggregation occurs as a consequence of perturbations in protein homeostasis that
can be triggered by environmental and cellular stresses. The accumulation of protein …

Genome architecture has proven to be critical in determining gene regulation across almost
all domains of life. While many of the key components and mechanisms of eukaryotic …

Decades of research have probed the interplay between chromatin (genomic DNA
associated with proteins and RNAs) and transcription by RNA polymerase (RNAP) in all …

Proteins have long been considered to be the most prominent factors regulating so-called
invasive genes involved in host-pathogen interactions. The possible role of small non …

The possible carrier role of Outer Membrane Vesicles (OMVs) for small regulatory
noncoding RNAs (sRNAs) has recently been demonstrated. Nevertheless, to perform their …

The RNA chaperone Hfq is an important bacterial post-transcriptional regulator. Most studies
on Hfq are focused on the role of this protein on small non-coding RNAs (sRNAs) and …

RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In
bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator. Using …

The bacterial chromosomic DNA is packed within a membrane-less structure, the nucleoid,
due to the association of DNA with proteins called Nucleoid Associated Proteins (NAPs) …

Hfq is a pleiotropic regulator that mediates several aspects of bacterial RNA metabolism.
The protein notably regulates translation efficiency and RNA decay in Gram-negative …

Inorganic polyphosphate (polyP), the first high-energy compound on earth, defies its
extreme compositional and structural simplicity with an astoundingly wide array of biological …