Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
Advanced collagen‐based biomaterials for regenerative biomedicine
In recent decades, collagen is one of the most versatile biomaterials used in biomedical
applications, mostly due to its biomimetic and structural composition in the extracellular …
applications, mostly due to its biomimetic and structural composition in the extracellular …
A new 3D printing strategy by harnessing deformation, instability, and fracture of viscoelastic inks
Direct ink writing (DIW) has demonstrated great potential as a multimaterial multifunctional
fabrication method in areas as diverse as electronics, structural materials, tissue …
fabrication method in areas as diverse as electronics, structural materials, tissue …
Soft network composite materials with deterministic and bio-inspired designs
Hard and soft structural composites found in biology provide inspiration for the design of
advanced synthetic materials. Many examples of bio-inspired hard materials can be found in …
advanced synthetic materials. Many examples of bio-inspired hard materials can be found in …
Large amplitude oscillatory shear flow: Microstructural assessment of polymeric systems
Since the first publications of large amplitude oscillatory shear (LAOS) responses of
polymeric materials in the 1960s, different approaches have been developed to express …
polymeric materials in the 1960s, different approaches have been developed to express …
Stem cell differentiation is regulated by extracellular matrix mechanics
Stem cells mechanosense the stiffness of their microenvironment, which impacts
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …
Stress controls the mechanics of collagen networks
Collagen is the main structural and load-bearing element of various connective tissues,
where it forms the extracellular matrix that supports cells. It has long been known that …
where it forms the extracellular matrix that supports cells. It has long been known that …
The role of network architecture in collagen mechanics
Collagen forms fibrous networks that reinforce tissues and provide an extracellular matrix for
cells. These networks exhibit remarkable strain-stiffening properties that tailor the …
cells. These networks exhibit remarkable strain-stiffening properties that tailor the …
Biomimetic strain-stiffening in chitosan self-healing hydrogels
Y Liu, SH Lin, WT Chuang, NT Dai… - ACS Applied Materials & …, 2022 - ACS Publications
The strain-stiffening and self-healing capabilities of biological tissues enable them to
preserve the structures and functions from deformation and damage. However …
preserve the structures and functions from deformation and damage. However …
Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion
H Ahmadzadeh, MR Webster… - Proceedings of the …, 2017 - National Acad Sciences
Cancer cell invasion from primary tumors is mediated by a complex interplay between
cellular adhesions, actomyosin-driven contractility, and the physical characteristics of the …
cellular adhesions, actomyosin-driven contractility, and the physical characteristics of the …