Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary

A Färkkilä, UM Haltia, J Tapper, MK McConechy… - Annals of …, 2017 - Taylor & Francis
Adult-type granulosa cell tumor is a clinically and molecularly unique subtype of ovarian
cancer. These tumors originate from the sex cord stromal cells of the ovary and represent 3 …

[HTML][HTML] The molecular mechanism of ovarian granulosa cell tumors

J Li, R Bao, S Peng, C Zhang - Journal of ovarian research, 2018 - Springer
Over these years, more and more sex cord-stromal tumors have been reported. Granulosa
cell tumor (GCT) is a rare tumor in ovaries, accounts for 2% to 5% of ovarian cancers. The …

Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease

JA Pilsworth, DR Cochrane, SJ Neilson… - The Journal of …, 2021 - Wiley Online Library
Adult‐type granulosa cell tumors (aGCTs) account for 90% of malignant ovarian sex cord‐
stromal tumors and 2–5% of all ovarian cancers. These tumors are usually diagnosed at an …

Granulosa cell tumor of ovary: A systematic review of recent evidence

G Levin, R Zigron, R Haj-Yahya, LS Matan… - European Journal of …, 2018 - Elsevier
Materials and methods Manuscripts cited in this review were identified by search in the
PubMed electronic databases. Search was performed using a broad range of combinations …

Effect of weekly paclitaxel with or without bevacizumab on progression-free rate among patients with relapsed ovarian sex cord-stromal tumors: the ALIENOR/ENGOT …

I Ray-Coquard, P Harter, D Lorusso, C Dalban… - JAMA …, 2020 - jamanetwork.com
Importance To our knowledge, this is the first randomized trial in sex cord-stromal tumors,
and it establishes weekly paclitaxel as standard-of-care therapy after platinum-based …

Progress in the management of ovarian granulosa cell tumor: A review

J Li, R Chu, Z Chen, J Meng, S Yao… - Acta obstetricia et …, 2021 - Wiley Online Library
Ovarian granulosa cell tumor (GCT) is a rare, low‐grade malignant tumor that accounts for
70% of the sex cord‐stromal tumors. It has two histopathologic types with different clinical …

[HTML][HTML] Molecular pathways and targeted therapies for malignant ovarian germ cell tumors and sex cord–stromal tumors: a contemporary review

A Maoz, K Matsuo, MA Ciccone, S Matsuzaki, M Klar… - Cancers, 2020 - mdpi.com
Non-epithelial ovarian tumors are heterogeneous and account for approximately 10% of
ovarian malignancies. The most common subtypes of non-epithelial ovarian tumors arise …

[HTML][HTML] Bevacizumab Efficiently Inhibits VEGF-Associated Cellular Processes in Equine Umbilical Vein Endothelial Cells: An In Vitro Characterization

U Lessiak, B Pratscher, A Tichy, B Nell - Veterinary Sciences, 2023 - mdpi.com
Simple Summary Angiogenesis, the sprouting of new capillaries from existing vessels, plays
a crucial role in various physiological processes. Pathological vascularization, as seen in …

[HTML][HTML] Kisspeptin-10 inhibits OHSS by suppressing VEGF secretion

J Zhai, J Liu, S Zhao, H Zhao, ZJ Chen, Y Du… - …, 2017 - rep.bioscientifica.com
The aim of the present study was to elucidate the effects of kisspeptin-10 (Kp-10) on ovarian
hyperstimulation syndrome (OHSS) and its related mechanism in OHSS rat models, human …

Delta-9-tetrahydrocannabinol increases vascular endothelial growth factor (VEGF) secretion through a cyclooxygenase-dependent mechanism in rat granulosa cells

AA Martínez-Peña, JJ Petrik, DB Hardy… - Reproductive …, 2022 - Elsevier
While the effects of delta-9-tetrahydrocannabinol (THC), the psychoactive component of
cannabis, have been studied extensively in the central nervous system, there is limited …