Large-conductance Ca2+-and voltage-activated K+ (BK) channels play many physiological
roles ranging from the maintenance of smooth muscle tone to hearing and neurosecretion …

The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …

Abstract The Ca2+-activated K+ channel, Slo1, has an unusually large conductance and
contains a voltage sensor and multiple chemical sensors. Dual activation by membrane …

De novo engineering of gene circuits inside cells is extremely difficult,,,,,,,,, and efforts to
realize predictable and robust performance must deal with noise in gene expression and …

Novel KCNMA1 variants, encoding the BK K+ channel, are associated with a debilitating
dyskinesia and epilepsy syndrome. Neurodevelopmental delay, cognitive disability, and …

Abstract High-conductance,'big'potassium (BK) channels encoded by the Slo gene family
are among the largest and most complex of the extended family of potassium channels. The …

Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

Piezo1 and Piezo2 encode mechanically activated cation channels that function as
mechanotransducers involved in vascular system development and touch sensing …

Large conductance, Ca 2+-activated potassium (BK) channels are widely expressed
throughout the animal kingdom and play important roles in many physiological processes …

Potassium channels are tetrameric membrane proteins that selectively conduct K+ across
cellular membranes. With 78 family members, K+ channels make up about half of the …