[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine
MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease
SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
Metals in Alzheimer's disease
The role of metals in the pathogenesis of Alzheimer's disease (AD) is still debated. Although
previous research has linked changes in essential metal homeostasis and exposure to …
previous research has linked changes in essential metal homeostasis and exposure to …
[HTML][HTML] Autophagy and beyond: Unraveling the complexity of UNC-51-like kinase 1 (ULK1) from biological functions to therapeutic implications
L Zou, M Liao, Y Zhen, S Zhu, X Chen, J Zhang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Abstract UNC-51-like kinase 1 (ULK1), as a serine/threonine kinase, is an autophagic
initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in yeast …
initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in yeast …
Lysosome-targeted fluorescent probes: Design mechanism and biological applications
X Duan, Q Tong, C Fu, L Chen - Bioorganic Chemistry, 2023 - Elsevier
As an integral organelle in the eukaryote, the lysosome is the degradation center and
metabolic signal center in living cells, and partakes in significant physiological processes …
metabolic signal center in living cells, and partakes in significant physiological processes …
Recent advances in electrochemical biosensors for the detection of Aβ42, a biomarker for Alzheimer disease diagnosis
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a long latency in
the" prodromal" stage, for which there are currently no effective treatments. It is generally …
the" prodromal" stage, for which there are currently no effective treatments. It is generally …
Metal–Organic Frameworks‐Based Nanoplatforms for the Theranostic Applications of Neurological Diseases
H Niu, H Bu, J Zhao, Y Zhu - Small, 2023 - Wiley Online Library
Neurological diseases are the foremost cause of disability and the second leading cause of
death worldwide. Owing to the special microenvironment of neural tissues and biological …
death worldwide. Owing to the special microenvironment of neural tissues and biological …
A survey of deep learning for alzheimer's disease
Alzheimer's and related diseases are significant health issues of this era. The
interdisciplinary use of deep learning in this field has shown great promise and gathered …
interdisciplinary use of deep learning in this field has shown great promise and gathered …
Trilateral association of autophagy, mTOR and Alzheimer's disease: Potential pathway in the development for Alzheimer's disease therapy
The primary and considerable weakening event affecting elderly individuals is age-
dependent cognitive decline and dementia. Alzheimer's disease (AD) is the chief cause of …
dependent cognitive decline and dementia. Alzheimer's disease (AD) is the chief cause of …
Hederagenin improves Alzheimer's disease through PPARα/TFEB-mediated autophagy
Z Xie, J Zhao, L Wu, S Chu, Z Cui, Y Sun, H Wang… - Phytomedicine, 2023 - Elsevier
Background Autophagic flux is coordinated by a network of master regulatory genes, which
centered on transcription factor EB (TFEB). The disorders of autophagic flux are closely …
centered on transcription factor EB (TFEB). The disorders of autophagic flux are closely …