Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, is overexpressed and
activated in many cancer types. FAK regulates diverse cellular processes, including growth …

Cancer progression including proliferation, metastasis, and chemoresistance has become a
serious hindrance to cancer therapy. This phenomenon mainly derives from the innate …

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase over-expressed and
activated in both adult and pediatric cancers, where it plays important roles in the regulation …

LncRNAs have become a hot topic in various cancer-related researches. Radio-resistance
is a great threat for cancer therapy. However, how lncRNAs affect the radio-resistance in …

Soft tissue sarcomas (STSs) are an uncommon group of solid tumors that can arise
throughout the human lifespan. Despite their commonality as non-bony cancers that develop …

Focal adhesion kinase (FAK) and its close paralogue, proline-rich tyrosine kinase 2 (PYK2),
are key regulators of aggressive spreading and metastasis of cancer cells. While targeted …

Abstract miRNAs have attracted increased attention as biomarkers, which have strong
associations with diseases like cancers. Herein, we have constructed DNA four-way junction …

Formaldehyde is an environmental and occupational chemical carcinogen implicated in the
damage of proteins and nucleic acids. However, whether formaldehyde provokes …

Well-differentiated liposarcoma (WDLPS) is the most frequent subtype of liposarcoma and
may transform into dedifferentiated liposarcoma (DDLPS) which is a more aggressive …

Obesity has become a public health problem worldwide. Compared with Europe, people in
Asia tend to suffer from type 2 diabetes with a lower body mass index (BMI). Genome-wide …