Application of stem cells in peripheral nerve regeneration

S Yi, Y Zhang, X Gu, L Huang, K Zhang, T Qian… - Burns & …, 2020 - academic.oup.com
Traumatic peripheral nerve injury is a worldwide clinical issue with high morbidity. The
severity of peripheral nerve injury can be classified as neurapraxia, axonotmesis or …

Conductive biomaterials as nerve conduits: recent advances and future challenges

P Zarrintaj, E Zangene, S Manouchehri… - Applied Materials …, 2020 - Elsevier
Millions of people around the world are in distress due to neurodegenerative disorders.
There have been continued attempts to design biomaterial-based therapies for the …

[HTML][HTML] Biopolymer-based composites for tissue engineering applications: A basis for future opportunities

P Zarrintaj, F Seidi, MY Azarfam, MK Yazdi… - Composites Part B …, 2023 - Elsevier
Biomimetic scaffolds supporting tissue regeneration are complex materials with
multifunctional characteristics. The unique biocompatibility and biodegradability of …

Adaptable microporous hydrogels of propagating NGF‐gradient by injectable building blocks for accelerated axonal outgrowth

RS Hsu, PY Chen, JH Fang, YY Chen… - Advanced …, 2019 - Wiley Online Library
Injectable hydrogels in regeneration medicine can potentially mimic hierarchical natural
living tissue and fill complexly shaped defects with minimally invasive implantation …

Bio-scaffolds as cell or exosome carriers for nerve injury repair

R Poongodi, YL Chen, TH Yang, YH Huang… - International journal of …, 2021 - mdpi.com
Central and peripheral nerve injuries can lead to permanent paralysis and organ
dysfunction. In recent years, many cell and exosome implantation techniques have been …

An electroactive alginate hydrogel nanocomposite reinforced by functionalized graphite nanofilaments for neural tissue engineering

S Homaeigohar, TY Tsai, TH Young, HJ Yang… - Carbohydrate …, 2019 - Elsevier
To address the need to biodegradable, electroactive conduits accelerating nerve
regeneration, here we develop a nanocomposite hydrogel made of alginate reinforced by …

Repair strategies for injured peripheral nerve

C Raza, HA Riaz, R Anjum - Life sciences, 2020 - Elsevier
Compromised functional regains in about half of the patients following surgical nerve repair
pose a serious socioeconomic burden to the society. Although surgical strategies such as …

An update–tissue engineered nerve grafts for the repair of peripheral nerve injuries

NP Patel, KA Lyon, JH Huang - Neural regeneration research, 2018 - journals.lww.com
Peripheral nerve injuries (PNI) are caused by a range of etiologies and result in a broad
spectrum of disability. While nerve autografts are the current gold standard for the …

The interaction of stem cells and vascularity in peripheral nerve regeneration

S Saffari, TM Saffari, DJO Ulrich… - Neural Regeneration …, 2021 - journals.lww.com
The degree of nerve regeneration after peripheral nerve injury can be altered by the
microenvironment at the site of injury. Stem cells and vascularity are postulated to be a part …

[HTML][HTML] Additive manufacturing of peripheral nerve conduits–fabrication methods, design considerations and clinical challenges

A Zennifer, M Thangadurai, D Sundaramurthi… - SLAS technology, 2023 - Elsevier
Tissue-engineered nerve guidance conduits (NGCs) are a viable clinical alternative to
autografts and allografts and have been widely used to treat peripheral nerve injuries (PNIs) …