Biomaterials in tendon and skeletal muscle tissue engineering: current trends and challenges
Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …
Tendon tissue engineering: An overview of biologics to promote tendon healing and repair
Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …
In vitro innovation of tendon tissue engineering strategies
MR Citeroni, MC Ciardulli, V Russo… - International journal of …, 2020 - mdpi.com
Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …
Tendon and cytokine marker expression by human bone marrow mesenchymal stem cells in a hyaluronate/poly-lactic-co-glycolic acid (PLGA)/fibrin three-dimensional …
We developed a (three-dimensional) 3D scaffold, we named HY-FIB, incorporating a force-
transmission band of braided hyaluronate embedded in a cell localizing fibrin hydrogel and …
transmission band of braided hyaluronate embedded in a cell localizing fibrin hydrogel and …
Growth factor delivery strategies for rotator cuff repair and regeneration
A Prabhath, VN Vernekar, E Sanchez… - International journal of …, 2018 - Elsevier
The high incidence of degenerative tears and prevalence of retears (20–95%) after surgical
repair makes rotator cuff injuries a significant health problem. This high retear rate is …
repair makes rotator cuff injuries a significant health problem. This high retear rate is …
Mechanical activation drives tenogenic differentiation of human mesenchymal stem cells in aligned dense collagen hydrogels
Tendons are force transmitting mechanosensitive tissues predominantly comprised of highly
aligned collagen type I fibres. In this study, the recently introduced gel aspiration-ejection …
aligned collagen type I fibres. In this study, the recently introduced gel aspiration-ejection …
Current pharmacological approaches to the treatment of tendinopathy
R Aicale, RD Bisaccia, A Oliviero, F Oliva… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Tendinopathies are common in elite and recreational athletes: traditionally
considered overuse injuries, they involve excessive tensile loading and subsequent …
considered overuse injuries, they involve excessive tensile loading and subsequent …
Tendon tissue engineering: Current progress towards an optimized tenogenic differentiation protocol for human stem cells
Tendons are integral to our daily lives by allowing movement and locomotion but are
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …
Advanced strategies for constructing interfacial tissues of bone and tendon/ligament
W Luo, Y Wang, Q Han, Z Wang, J Jiao… - Journal of Tissue …, 2022 - journals.sagepub.com
Enthesis, the interfacial tissue between a tendon/ligament and bone, exhibits a complex
histological transition from soft to hard tissue, which significantly complicates its repair and …
histological transition from soft to hard tissue, which significantly complicates its repair and …
A standalone bioreactor system to deliver compressive load under perfusion flow to hBMSC-seeded 3D chitosan-graphene templates
The availability of engineered biological tissues holds great potential for both clinical
applications and basic research in a life science laboratory. A prototype standalone …
applications and basic research in a life science laboratory. A prototype standalone …