Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary tract tumor.
Unfortunately, only a small population of cancer patients is acceptable for the surgical …

Cholangiocarcinoma is characterized by a poor prognosis with limited treatment and
management options. Chemotherapy using gemcitabine with cisplatin is the only available …

Background We conducted a phase II study of the combination of pembrolizumab with
capecitabine and oxaliplatin (CAPOX) in patients with advanced biliary tract carcinoma …

Biliary tract cancers (BTCs) are a heterogeneous group of adenocarcinomas that originate
from the epithelial lining of the biliary tree. BTCs are characterized by presentation with …

Background: Biliary tract cancers (BTCs) include cholangiocarcinomas and gallbladder
cancers usually present at an advanced stage, which are considered resectable in less than …

Simple Summary Biliary tract cancers (BTCs) are a rare pathology. In the era of precision
oncology, the development of next-generation sequencing (NGS) allowed a better …

Background and aims Dickkopf‐1 (DKK1) is associated with poor prognosis in intrahepatic
cholangiocarcinoma (iCCA), but the mechanisms behind this are unclear. Here, we show …

Background: Cholangiocarcinoma (CCA) encompasses a heterogeneous group of
malignant tumors with dismal prognosis and increasing incidence worldwide. Both late …

Background Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) has
shown remarkable results in malignant melanoma (MM), while studies on the potential in …

The introduction of next-generation sequencing (NGS) in the molecular diagnostic
armamentarium is deeply changing pathology practice and laboratory frameworks. NGS …