Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in both
men and women in developed societies. Age is the greatest risk factor for CVD due largely …

Nicotinamide adenine dinucleotide (NAD+) has emerged as a critical co-substrate for
enzymes involved in the beneficial effects of regular calorie restriction on healthspan. As …

Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

In recent years, great emphasis has been placed on the role of arterial stiffness in the
development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is …

disease identified by the epidemiologists. If the variable is perceived as beneficial or
deleterious with respect to cardiovascular structure or function, those with extreme measures …

We recognize that increased systolic pressure is the most challenging form of hypertension
today and that pulse pressure as an independent cardiovascular risk factor has focused …

Background—A reduction in compliance of the large-sized cardiothoracic (central) arteries is
an independent risk factor for the development of cardiovascular disease with advancing …

Background Arterial stiffness is an important risk factor for cardiovascular disease. Carotid-
femoral pulse wave velocity (cfPWV) is the most recognized and established index of arterial …

We hypothesized that curcumin would improve resistance and conduit artery endothelial
function and large elastic artery stiffness in healthy middle-aged and older adults. Thirty-nine …