Health agencies worldwide have historically cautioned that electric fans accelerate body-
heat gain during hot weather and heatwaves (typically in air temperatures≥ 35° C) …

The world is experiencing increased frequency, duration, and severity of life-threatening
heat extremes. Most hospitalizations and excess deaths during extreme heat events are …

Background: Health agencies recommend that homes of heat-vulnerable occupants (eg,
older adults) be maintained below 24–28° C to prevent heat-related mortality and morbidity …

With rising global temperatures, heat-related mortality is increasing, particularly among older
adults. Although this is often attributed to declines in thermoregulatory function, little is …

The significance of the thermo-physiological determinants of heat-related deaths has been
recognized since antiquity. Still, the impact of heat on human health in the modern era is …

Older adults are at greater risk of heat-related morbidity and mortality during heat waves,
which is commonly linked to impaired thermoregulation. However, little is known about the …

We tested whether older adults, compared with young adults, exhibit greater gastrointestinal
permeability and kidney injury during heat stress. Nine young (32±3 years) and nine older …

Heat waves can cause dangerous elevations in body temperature that can compromise
cellular function and increase the risk of heat stroke and major cardiovascular events …

Heat stress induced damage to the gastrointestinal barrier can induce local and systemic
inflammatory reactions implicated in heat-stroke. Gastrointestinal barrier damage has been …

Hyperthermia is known as a hyperadrenergic state, yet there is a lack of data on the
sympathetic responses to ambient heat stress in humans. Therefore, we investigated the …