COVID-19 therapeutic potential of natural products

Z Low, R Lani, V Tiong, C Poh, S AbuBakar… - International Journal of …, 2023 - mdpi.com
Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are
now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

The emerging role of neutrophils in the pathogenesis of thrombosis in COVID-19

V Iliadi, I Konstantinidou, K Aftzoglou, S Iliadis… - International journal of …, 2021 - mdpi.com
Previous studies have shown that COVID-19 leads to thrombotic complications, which have
been associated with high morbidity and mortality rates. Neutrophils are the largest …

Stability and reactivity study of bio-molecules brucine and colchicine towards electrophile and nucleophile attacks: Insight from DFT and MD simulations

YS Mary, YS Mary, S Armaković, SJ Armaković… - Journal of Molecular …, 2021 - Elsevier
A set of molecular descriptors have been calculated and used in order to identify the most
reactive parts of bioactive molecules, brucine (BRU) and colchicine (COL). Comparison of …

Colchicine is safe though ineffective in the treatment of severe COVID-19: a randomized clinical trial (COLCHIVID)

A Absalon-Aguilar, M Rull-Gabayet… - Journal of General …, 2022 - Springer
Background Colchicine is an available, safe, and effective anti-inflammatory drug and has
been suggested as a COVID-19 treatment, but its usefulness in hospitalized severe COVID …

Review of hydroxychloroquine cardiotoxicity: lessons from the COVID-19 pandemic

LR Gagnon, C Sadasivan, H Yogasundaram… - Current Heart Failure …, 2022 - Springer
Abstract Purpose of Review The coronavirus disease 2019 (COVID-19) pandemic has
popularized the usage of hydroxychloroquine and chloroquine (HCQ/CQ) as treatments for …

Skeletal muscle manifestations and creatine kinase in COVID-19

SA Friedman, Z Charmchi, M Silver… - The …, 2022 - journals.sagepub.com
Background and Purpose Skeletal muscle symptoms and elevated creatine kinase (CK)
levels have been consistently reported as part of the COVID-19 disease process. Previous …

Cardiovascular issues in rheumatic diseases

O Zimba, AY Gasparyan - Clinical Rheumatology, 2023 - Springer
Cardiovascular disease is a major cause of morbidity and mortality in rheumatic diseases,
particularly rheumatoid arthritis and systemic lupus erythematosus. Timely detection and …

Determination of Therapeutic and Safety Effects of Zygophyllum coccineum Extract in Induced Inflammation in Rats

M Yosri, MM Elaasser, MM Abdel-Aziz… - BioMed Research …, 2022 - Wiley Online Library
Background. Z. coccineum is a facultative plant with many medicinal applications. This study
examined the anti‐inflammatory activity of Zygophyllum coccineum (Z. coccineum) in an …

Challenges and opportunities from targeting inflammatory responses to SARS-CoV-2 infection: a narrative review

V Lariccia, S Magi, T Serfilippi, M Toujani… - Journal of Clinical …, 2020 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) is a global pandemic that continues to
sweep across the world, posing an urgent need for effective therapies and prevention of the …

Population-level interest in anti-rheumatic drugs in the COVID-19 era: insights from Google Trends

S Kardeş, AS Kuzu, H Pakhchanian, R Raiker… - Clinical …, 2021 - Springer
Introduction/objective The general public may utilize online information through search
engines for implications and risks of some anti-rheumatic drugs. These drugs have been …