Abstract The 1, 3, 4‐oxadiazole nucleus is a biologically imperative scaffold possesses
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …

Oxadiazole nucleus shows a broad spectrum of pharmaceutical applications. Thus, in recent
years scientists have developed various new methods for the synthesis of its derivatives …

A series of 5-(3-indolyl)-2-substituted-1, 3, 4-thiadiazoles 5a–m were synthesized and their
cytotoxicity analyzed against six human cancer cell lines. The reaction of indole-3-carboxylic …

A series of indolyl chalcones were synthesized and evaluated in vitro for their anticancer
activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j …

The synthetic strategies and characterization of some novel 1, 3, 4-oxadiazole derivatives
carrying different pharmacophores and heterocyclic rings that are relevant to potential …

A series of thiazole clubbed 1, 3, 4-oxadiazole derivatives (5a–l) have been synthesized and
characterized by IR, 1 H NMR, 13 C NMR and mass spectral analysis. Synthesized …

On the basis of the principle of combination of active structural moieties, a modified and
efficient synthetic method for three series of novel indole-based 1, 3, 4-oxadiazoles is …

Starting from 4-(1H-benzo [d] imidazol-2-yl)-4-oxobutanehydrazide (1), twenty new 1-(1H-
benzo [d] imidazol-2-yl)-3-(1, 3, 4-oxadiazol-5-substituted derivatives-2-yl) propan-1-ones …

In recent years, indole-indazolyl hydrazide-hydrazone derivatives with strong cell growth
inhibition and apoptosis induction characteristics are being strongly screened for their …

Aberrant activation of NF-κB is linked with the progression of human malignancies including
hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential …