1, 3, 4‐oxadiazole and its derivatives: A review on recent progress in anticancer activities
A Vaidya, D Pathak, K Shah - Chemical biology & drug design, 2021 - Wiley Online Library
Abstract The 1, 3, 4‐oxadiazole nucleus is a biologically imperative scaffold possesses
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …
Review of synthesis of 1, 3, 4-oxadiazole derivatives
KD Patel, SM Prajapati, SN Panchal… - Synthetic …, 2014 - Taylor & Francis
Oxadiazole nucleus shows a broad spectrum of pharmaceutical applications. Thus, in recent
years scientists have developed various new methods for the synthesis of its derivatives …
years scientists have developed various new methods for the synthesis of its derivatives …
Synthesis and anticancer activity of 5-(3-indolyl)-1, 3, 4-thiadiazoles
A series of 5-(3-indolyl)-2-substituted-1, 3, 4-thiadiazoles 5a–m were synthesized and their
cytotoxicity analyzed against six human cancer cell lines. The reaction of indole-3-carboxylic …
cytotoxicity analyzed against six human cancer cell lines. The reaction of indole-3-carboxylic …
Synthesis and biological evaluation of indolyl chalcones as antitumor agents
D Kumar, NM Kumar, K Akamatsu, E Kusaka… - Bioorganic & medicinal …, 2010 - Elsevier
A series of indolyl chalcones were synthesized and evaluated in vitro for their anticancer
activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j …
activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j …
Synthesis and antitumor evaluation of some new 1, 3, 4-oxadiazole-based heterocycles
The synthetic strategies and characterization of some novel 1, 3, 4-oxadiazole derivatives
carrying different pharmacophores and heterocyclic rings that are relevant to potential …
carrying different pharmacophores and heterocyclic rings that are relevant to potential …
Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1, 3, 4-oxadiazoles
A series of thiazole clubbed 1, 3, 4-oxadiazole derivatives (5a–l) have been synthesized and
characterized by IR, 1 H NMR, 13 C NMR and mass spectral analysis. Synthesized …
characterized by IR, 1 H NMR, 13 C NMR and mass spectral analysis. Synthesized …
Synthesis and antifungal activity of 3-(1, 3, 4-oxadiazol-5-yl)-indoles and 3-(1, 3, 4-oxadiazol-5-yl) methyl-indoles
MZ Zhang, N Mulholland, D Beattie, D Irwin… - European Journal of …, 2013 - Elsevier
On the basis of the principle of combination of active structural moieties, a modified and
efficient synthetic method for three series of novel indole-based 1, 3, 4-oxadiazoles is …
efficient synthetic method for three series of novel indole-based 1, 3, 4-oxadiazoles is …
Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents
Starting from 4-(1H-benzo [d] imidazol-2-yl)-4-oxobutanehydrazide (1), twenty new 1-(1H-
benzo [d] imidazol-2-yl)-3-(1, 3, 4-oxadiazol-5-substituted derivatives-2-yl) propan-1-ones …
benzo [d] imidazol-2-yl)-3-(1, 3, 4-oxadiazol-5-substituted derivatives-2-yl) propan-1-ones …
Synthesis, antiproliferative and apoptosis induction potential activities of novel bis (indolyl) hydrazide-hydrazone derivatives
In recent years, indole-indazolyl hydrazide-hydrazone derivatives with strong cell growth
inhibition and apoptosis induction characteristics are being strongly screened for their …
inhibition and apoptosis induction characteristics are being strongly screened for their …
Novel 1, 3, 4-oxadiazole induces anticancer activity by targeting NF-κB in hepatocellular carcinoma cells
CD Mohan, NC Anilkumar, S Rangappa… - Frontiers in …, 2018 - frontiersin.org
Aberrant activation of NF-κB is linked with the progression of human malignancies including
hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential …
hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential …