[HTML][HTML] Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management
EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
[HTML][HTML] Application of targeted maximum likelihood estimation in public health and epidemiological studies: a systematic review
Purpose The targeted maximum likelihood estimation (TMLE) statistical data analysis
framework integrates machine learning, statistical theory, and statistical inference to provide …
framework integrates machine learning, statistical theory, and statistical inference to provide …
[HTML][HTML] Causal inference using observational intensive care unit data: a scoping review and recommendations for future practice
This scoping review focuses on the essential role of models for causal inference in shaping
actionable artificial intelligence (AI) designed to aid clinicians in decision-making. The …
actionable artificial intelligence (AI) designed to aid clinicians in decision-making. The …
Postoperative acute respiratory distress syndrome in randomized controlled trials
Background Acute respiratory distress syndrome is a potentially fatal postoperative
complication. We aimed to estimate temporal trends of the representation of patients with …
complication. We aimed to estimate temporal trends of the representation of patients with …
Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials
Background Efficiency of randomised clinical trials of acute respiratory distress syndrome
(ARDS) depends on the fraction of deaths attributable to ARDS (AFARDS) to which …
(ARDS) depends on the fraction of deaths attributable to ARDS (AFARDS) to which …
[HTML][HTML] The roles of tissue-resident macrophages in sepsis-associated organ dysfunction
Y Gao, X Tian, X Zhang, GDM Nkoua, F Chen, Y Liu… - Heliyon, 2023 - cell.com
Sepsis, a syndrome caused by a dysregulated host response to infection and characterized
by life-threatening organ dysfunction, particularly septic shock and sepsis-associated organ …
by life-threatening organ dysfunction, particularly septic shock and sepsis-associated organ …
[HTML][HTML] Attributable mortality of ARDS among critically ill patients with sepsis: a multicenter, retrospective cohort study
DH Wang, HM Jia, X Zheng, XM Xi, Y Zheng… - BMC Pulmonary …, 2024 - Springer
Background Both sepsis and acute respiratory distress syndrome (ARDS) are common
severe diseases in the intensive care unit (ICU). There is no large-scale multicenter study to …
severe diseases in the intensive care unit (ICU). There is no large-scale multicenter study to …
[HTML][HTML] Rapidly improving acute respiratory distress syndrome in COVID-19: a multi-centre observational study
E Gavrielatou, K Vaporidi, V Tsolaki, N Tserlikakis… - Respiratory …, 2022 - Springer
Background Before the pandemic of coronavirus disease (COVID-19), rapidly improving
acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been …
acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been …
[HTML][HTML] The ROCK-ezrin signaling pathway mediates LPS-induced cytokine production in pulmonary alveolar epithelial cells
N Ding, P Li, H Li, Y Lei, Z Zhang - Cell Communication and Signaling, 2022 - Springer
Background Ezrin/radixin/moesin (ERM) proteins are members of the protein 4.1 superfamily
and function as linkers that connect the actin cytoskeleton to the plasma membrane of cells …
and function as linkers that connect the actin cytoskeleton to the plasma membrane of cells …
Intubation timing in COVID-19 based on ROX index and association with patient outcomes
BACKGROUND: Timing of intubation in COVID-19 is controversial. We sought to determine
the association of the ROX (Respiratory rate–OXygenation) index defined as S pO 2 divided …
the association of the ROX (Respiratory rate–OXygenation) index defined as S pO 2 divided …