Children born small for gestational age: differential diagnosis, molecular genetic evaluation, and implications

MJJ Finken, M van der Steen, CCJ Smeets… - Endocrine …, 2018 - academic.oup.com
Children born small for gestational age (SGA), defined as a birth weight and/or length
below− 2 SD score (SDS), comprise a heterogeneous group. The causes of SGA are …

The physiology of intrapartum fetal compromise at term

JM Turner, MD Mitchell, SS Kumar - American journal of obstetrics and …, 2020 - Elsevier
Uterine contractions in labor result in a 60% reduction in uteroplacental perfusion, causing
transient fetal and placental hypoxia. A healthy term fetus with a normally developed …

[HTML][HTML] Development and validation of a spontaneous preterm delivery predictor in asymptomatic women

GR Saade, KA Boggess, SA Sullivan… - American journal of …, 2016 - Elsevier
Background Preterm delivery remains the leading cause of perinatal mortality. Risk factors
and biomarkers have traditionally failed to identify the majority of preterm deliveries …

Circulating biomarkers associated with placental dysfunction and their utility for predicting fetal growth restriction

J Hong, S Kumar - Clinical Science, 2023 - portlandpress.com
Fetal growth restriction (FGR) leading to low birth weight (LBW) is a major cause of neonatal
morbidity and mortality worldwide. Normal placental development involves a series of highly …

Maternal predictors of intrauterine growth restriction

I Cetin, C Mando, S Calabrese - Current Opinion in Clinical …, 2013 - journals.lww.com
Assessing nutritional and environmental factors associated with IUGR, and the molecular
mechanisms by which they may have a role in the disease onset, is necessary to provide …

Performance of a proteomic preterm delivery predictor in a large independent prospective cohort

GR Markenson, GR Saade, LC Laurent… - American journal of …, 2020 - Elsevier
Background Preterm birth remains a common and devastating complication of pregnancy.
There remains a need for effective and accurate screening methods for preterm birth. Using …

Progress in the understanding of the etiology and predictability of fetal growth restriction

L Tang, G He, X Liu, W Xu - Reproduction, 2017 - rep.bioscientifica.com
Fetal growth restriction (FGR) is defined as the failure of fetus to reach its growth potential for
various reasons, leading to multiple perinatal complications and adult diseases of fetal …

Identifying potential biomarkers related to pre-term delivery by proteomic analysis of amniotic fluid

S Hong, JE Lee, YM Kim, Y Park, JW Choi, KH Park - Scientific Reports, 2020 - nature.com
We sought to identify biomarkers in the amniotic fluid (AF) and specific signaling pathways
related to spontaneous preterm delivery (SPTD,< 34 weeks) in women with preterm labor …

A dual-binding magnetic immunoassay to predict spontaneous preterm birth

M Sveiven, A Gassman, J Rosenberg… - … in Bioengineering and …, 2023 - frontiersin.org
Complications posed by preterm birth (delivery before 37 weeks of pregnancy) are a leading
cause of newborn morbidity and mortality. The previous discovery and validation of an …

Insulin-like growth factor-binding protein 1 and 7 concentrations are lower in obese pregnant women, women with gestational diabetes and their fetuses

M Lappas - Journal of Perinatology, 2015 - nature.com
Objective: To determine the effect of pre-existing maternal obesity and gestational diabetes
mellitus (GDM) on the circulating levels of insulin growth factor-binding protein (IGFBPs) in …