The effect of dietary polyphenols on vascular health and hypertension: current evidence and mechanisms of action

G Grosso, J Godos, W Currenti, A Micek, L Falzone… - Nutrients, 2022 - mdpi.com
The aim of this review was to explore existing evidence from studies conducted on humans
and summarize the mechanisms of action of dietary polyphenols on vascular health, blood …

Kaempferol and atherosclerosis: From mechanism to medicine

M Chen, J Xiao, HR El-Seedi, KS Woźniak… - Critical Reviews in …, 2024 - Taylor & Francis
Natural products possess pleiotropic cardiovascular protective effects owing to their anti-
oxidation, anti-inflammation and anti-thrombotic properties. Kaempferol,(3, 5, 7-trihydroxy-2 …

Plant-food-derived bioactives in managing hypertension: From current findings to upcoming effective pharmacotherapies

M Butnariu, D Fratantonio… - Current topics in …, 2023 - ingentaconnect.com
A sedentary lifestyle has evoked a high risk of cardiovascular (CV) disease, diabetes, and
obesity, all of them with high morbimortality rates and with a common denominator …

[HTML][HTML] Vasorelaxing effect of Garcinia cowa leaf extract in rat thoracic aorta and its underlying mechanisms

S Yorsin, S Sriwiriyajan, W Chongsa - Journal of Traditional and …, 2023 - Elsevier
Background and aim The leaves of Garcinia cowa (G. cowa) are used in Thai traditional
medicine to improve blood circulation. However, there is no scientific evidence to confirm …

Insights to potential antihypertensive activity of berry fruits

M Yousefi, M Shadnoush, N Khorshidian… - Phytotherapy …, 2021 - Wiley Online Library
Hypertension is one of the main risk factors for cardiovascular disease and causes
widespread morbidity and mortality worldwide. Although several antihypertensive drugs …

New flavonoid-based compound synthesis strategy for antihypertensive drug development

YC Loh, SY Chan, WY Tew, CW Oo, MF Yam - Life Sciences, 2020 - Elsevier
Hypertension is one of the leading causes of mortality in relation to the cardiovascular
conditions and easily the most overlooked and poorly managed disease in mankind. With …

Mining Important Herb Combinations of Traditional Chinese Medicine against Hypertension Based on the Symptom‐Herb Network Combined with Network …

Z Sun, Y Xu, W An, S Bi, S Xu, R Zhang… - Evidence‐Based …, 2022 - Wiley Online Library
Although data mining methods are extensively used in the rule analysis of famous old
traditional Chinese medicine (TCM) experts' prescriptions for the treatment of hypertension …

In silico analysis of metabolites from Peruvian native plants as potential therapeutics against Alzheimer's disease

LD Goyzueta-Mamani, HL Barazorda-Ccahuana… - Molecules, 2022 - mdpi.com
Background: Despite research on the molecular bases of Alzheimer's disease (AD), effective
therapies against its progression are still needed. Recent studies have shown direct links …

Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological …

X Wang, J Li, L Liu, JM Kan, P Niu, ZQ Yu, C Ma… - … Medicine and Therapies, 2022 - Springer
Background and objective Epimedii has long been used as a traditional medicine in Asia for
the treatment of various common diseases, including Alzheimer's disease, cancer, erectile …

[HTML][HTML] Cucumber (Cucumis sativus L.) Fruit and Combination with Losartan Attenuate the Elevation of Blood Pressure in Hypertensive Rats Induced by Angiotensin II

T Hendrayana, K Yoana, IK Adnyana… - Journal of …, 2023 - ncbi.nlm.nih.gov
Objectives Cucumis sativus L.(C. sativus) is vegetable commonly used for managing blood
pressure and often consumed in combination with standard antihypertensive therapy …