Many studies have provided observational data on the association of obesity and thyroid
cancers, but only few of them propose mechanisms that would permit a better understanding …

Background Thyroid cancer is rapidly increasing in incidence worldwide in the past several
decades, same as the incidence of metabolic syndrome. We performed a system review and …

Abstract Background In Iran, lung cancer is the third most common type of cancer and its
prevalence is increasing rapidly. Identification informative genetic polymorphisms in cancer …

Globally, bladder cancer (BC) is one of the ten most common tumors. Obesity is a worldwide
problem associated with an increased BC risk. Considering that levels of leptin and/or its …

Liver cancer is the third most common cancer type and the second leading cause of deaths
in men. Large population studies have demonstrated remarkable gender disparities in the …

Background Adipokine leptin plays a crucial role in metabolic and reproductive functions.
Leptin receptor has a soluble form that binds to leptin, thus modulating its level in the …

Background Many studies have been conducted on the genetic and epigenetic etiology of
gestational diabetes mellitus (GDM) in the last two decades because of the disease's …

Background Neonatal adiposity has many determinants and may be a risk factor for future
obesity. Epigenetic regulation of metabolically important genes is a potential contributor …

Background High levels of serum leptin and low levels of serum adiponectin are strongly
correlated with obesity, a well-established risk factor for colorectal cancer (CRC). Growing …

Background Leptin (LEP) and LEP receptor (LEPR) polymorphisms may be associated with
the development of cancer. Methods In this study, we selected five functional LEP and LEPR …