[HTML][HTML] The role of inflammation in age-related macular degeneration

W Tan, J Zou, S Yoshida, B Jiang… - International journal of …, 2020 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a blinding eye disease which incidence
gradually increases with age. Inflammation participates in AMD pathogenesis, including …

Angiopoietin/Tie2 signalling and its role in retinal and choroidal vascular diseases: a review of preclinical data

AM Joussen, F Ricci, LP Paris, C Korn… - Eye, 2021 - nature.com
The ang opoietin/t yrosine kinase with i mmunoglobulin and e pidermal growth factor
homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development …

Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis

DY Shu, FJ Lovicu - Progress in retinal and eye research, 2017 - Elsevier
Wound healing is one of the most complex biological processes to occur in life. Repair of
tissue following injury involves dynamic interactions between multiple cell types, growth …

EMT and EndMT: emerging roles in age-related macular degeneration

DY Shu, E Butcher, M Saint-Geniez - International journal of molecular …, 2020 - mdpi.com
Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT)
are physiological processes required for normal embryogenesis. However, these processes …

PDGF in organ fibrosis

BM Klinkhammer, J Floege, P Boor - Molecular Aspects of Medicine, 2018 - Elsevier
Fibrosis is part of a tissue repair response to injury, defined as increased deposition of
extracellular matrix. In some instances, fibrosis is beneficial; however, in the majority of …

Role of epithelial-mesenchymal transition in retinal pigment epithelium dysfunction

M Zhou, JS Geathers, SL Grillo, SR Weber… - Frontiers in cell and …, 2020 - frontiersin.org
Retinal pigment epithelial (RPE) cells maintain the health and functional integrity of both
photoreceptors and the choroidal vasculature. Loss of RPE differentiation has long been …

Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune …

JHC Wong, JYW Ma, AI Jobling, A Brandli… - Frontiers in …, 2022 - frontiersin.org
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the
older population. Classical hallmarks of early and intermediate AMD are accumulation of …

Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives

L Tenbrock, J Wolf, S Boneva, A Schlecht… - Cell and Tissue …, 2022 - Springer
Age-related macular degeneration (AMD) is a progressive, degenerative disease of the
human retina which in its most aggressive form is associated with the formation of macular …

[HTML][HTML] Animal models of ocular angiogenesis: from development to pathologies

CH Liu, Z Wang, Y Sun, J Chen - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
Pathological angiogenesis in the eye is an important feature in the pathophysiology of many
vision-threatening diseases, including retinopathy of prematurity, diabetic retinopathy, and …

[WITHDRAWN] retinal vasculature in development and diseases

Y Sun, LEH Smith - Annual review of vision science, 2018 - annualreviews.org
This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …