Hardeveld F, Spijker J, De Graaf R, Nolen WA, Beekman ATF. Prevalence and predictors of
recurrence of major depressive disorder in the adult population. Objective: Knowledge of the …

Major depressive disorder (MDD) is prevalent. Although standards antidepressants are
more effective than placebo, up to 35% of patients do not respond to 4 or more conventional …

The gradual emergence of symptoms following exposure to traumatic events has presented
a major conceptual challenge to psychiatry. The mechanism that causes the progressive …

This pilot study investigated the effectiveness of Mindfulness-Based Cognitive Therapy
(MBCT), a treatment combining mindfulness meditation and interventions taken from …

Aims: The objectives of the present review were to summarise the key findings from the
clinical literature regarding the neurobiology of major depressive disorder (MDD) and their …

We review epidemiological studies of depression in Europe. Community surveys are
essential. Methodological differences in survey methods, instruments, nuances in language …

Little is known about the quantity or quality of residual depressive symptoms in patients with
major depressive disorder (MDD) who have responded but not remitted with antidepressant …

Effective treatment of severe or chronic unipolar depression requires the combination of
pharmacological and psychotherapeutic interventions, and demands a theoretical paradigm …

Partial remission from depression, with residual symptoms, is an important problem in
depression. This paper reviews the frequency and features of this outcome, and its …

Objectives: Numerous long‐term studies of depression in psychiatric settings have shown a
poor clinical outcome but little emphasis has been placed on psychosocial or functional …