α-Helical coiled coils were described more than 60 years ago as simple, repetitive structures
mediating oligomerization and mechanical stability. Over the past 20 years, however, they …

Abstract α-Helical coiled coils are versatile protein domains, supporting a wide range of
biological functions. Their fold is probably better understood than that of any other protein; …

The probability that a residue in a protein is part of a coiled-coil structure was assessed by
comparison of its flanking sequences with sequences of known coiled-coil proteins. This …

Low pH induces a conformational change in the influenza virus haemagglutinin, which then
mediates fusion of the viral and host cell membranes. The three-dimensional structure of a …

The x-ray crystal structure of a peptide corresponding to the leucine zipper of the yeast
transcriptional activator GCN4 has been determined at 1.8 angstrom resolution. The peptide …

M protein is a major virulence determinant for the group A streptococcus by virtue of its
ability to allow the organism to resist phagocytosis. Common in eucaryotes, the fibrillar …

Z/PI is a novel meiosis-specific gene required forchromosome synapsis and cell cycle
progression in S. cerevidae. z/p7 strains undergo homologous chromosome pairing, but are …

As myofibrils consist of a three-dimensional network of long, solid protein particles with the
shortest dimension of less than 20nm, the theoretical foundations of water-holding in meat …

Computational methods based on mathematically-defined measures of compositional
complexity have been developed to distinguish globular and non-globular regions of protein …

Publisher Summary This chapter describes methods for the precipitation of proteins for
preparative purposes. Proteins can be precipitated by causing perturbations in the solvent …