Current and future biomarkers in multiple sclerosis

J Yang, M Hamade, Q Wu, Q Wang, R Axtell… - International journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of
effective treatment for the progressive form of MS, partly due to insensitive readout for …

Molecular biomarkers in multiple sclerosis

T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous
system presenting with significant inter-and intraindividual heterogeneity. However, the …

[HTML][HTML] New promising therapeutic avenues of curcumin in brain diseases

T Benameur, G Giacomucci, MA Panaro, M Ruggiero… - Molecules, 2022 - mdpi.com
Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …

Immunology of multiple sclerosis

M Sospedra, R Martin - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …

A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking

CE Teunissen, A Petzold, JL Bennett, FS Berven… - Neurology, 2009 - AAN Enterprises
There is a long history of research into body fluid biomarkers in neurodegenerative and
neuroinflammatory diseases. However, only a few biomarkers in CSF are being used in …

Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis

D Miller, F Barkhof, X Montalban, A Thompson… - The Lancet …, 2005 - thelancet.com
In 85% of young adults with multiple sclerosis (MS), onset is a subacute clinically isolated
syndrome (CIS) of the optic nerves, brainstem, or spinal cord. Methods of assessing the …

Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls

A Keller, P Leidinger, J Lange, A Borries, H Schroers… - PloS one, 2009 - journals.plos.org
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system, which is heterogenous with respect to clinical manifestations and response …

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

M Khademi, I Kockum, ML Andersson… - Multiple Sclerosis …, 2011 - journals.sagepub.com
Background: Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the
cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of …

Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging

EM Haacke, M Makki, Y Ge… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To investigate whether the variable forms of putative iron deposition seen with
susceptibility weighted imaging (SWI) will lead to a set of multiple sclerosis (MS) lesion …