Clostridium difficile colitis: pathogenesis and host defence

MC Abt, PT McKenney, EG Pamer - Nature Reviews Microbiology, 2016 - nature.com
Clostridium difficile is a major cause of intestinal infection and diarrhoea in individuals
following antibiotic treatment. Recent studies have begun to elucidate the mechanisms that …

Fate of Clostridia and other spore-forming Firmicute bacteria during feedstock anaerobic digestion and aerobic composting

J Subirats, H Sharpe, E Topp - Journal of Environmental Management, 2022 - Elsevier
Pathogenic spore-forming Firmicutes are commonly present in animal and human wastes
that are used as fertilizers in crop production. Pre-treatments of organic waste prior to land …

Bacteriophage Combinations Significantly Reduce Clostridium difficile Growth In Vitro and Proliferation In Vivo

JY Nale, J Spencer, KR Hargreaves… - Antimicrobial agents …, 2016 - Am Soc Microbiol
The microbiome dysbiosis caused by antibiotic treatment has been associated with both
susceptibility to and relapse of Clostridium difficile infection (CDI). Bacteriophage (phage) …

Genome Analysis of Clostridium difficile PCR Ribotype 014 Lineage in Australian Pigs and Humans Reveals a Diverse Genetic Repertoire and Signatures of Long …

DR Knight, MM Squire, DA Collins… - Frontiers in microbiology, 2017 - frontiersin.org
Clostridium difficile PCR ribotype (RT) 014 is well-established in both human and porcine
populations in Australia, raising the possibility that C. difficile infection (CDI) may have a …

Advances in the diagnosis and treatment of Clostridium difficile infections

Z Peng, L Ling, CW Stratton, C Li… - Emerging microbes & …, 2018 - Taylor & Francis
Clostridium difficile is a leading cause of antibiotic-associated diarrhea worldwide. The
diagnosis of C. difficile infection (CDI) requires both clinical manifestations and a positive …

An update on Clostridium difficile toxinotyping

M Rupnik, S Janezic - Journal of clinical microbiology, 2016 - Am Soc Microbiol
Toxinotyping is a PCR-restriction fragment length polymorphism (RFLP)-based method for
differentiation of Clostridium difficile strains according to the changes in the pathogenicity …

Clostridium difficile infection: evolution, phylogeny and molecular epidemiology

B Elliott, GO Androga, DR Knight, TV Riley - Infection, Genetics and …, 2017 - Elsevier
Over the recent decades, Clostridium difficile infection (CDI) has emerged as a global public
health threat. Despite growing attention, C. difficile remains a poorly understood pathogen …

The zoonotic potential of Clostridium difficile from small companion animals and their owners

D Rabold, W Espelage, M Abu Sin, T Eckmanns… - PloS one, 2018 - journals.plos.org
Background Clostridium difficile infections (CDI) in humans range from asymptomatic
carriage to life-threatening intestinal disease. Findings on C. difficile in various animal …

Clostridium difficile in Food and Animals: A Comprehensive Review

C Rodriguez, B Taminiau, J Van Broeck… - … Infectious Diseases and …, 2016 - Springer
Zoonoses are infections or diseases that can be transmitted between animals and humans
through direct contact, close proximity or the environment. Clostridium difficile is ubiquitous …

A review of Clostridioides [Clostridium] difficile occurrence through the food chain

C Candel-Pérez, G Ros-Berruezo, C Martínez-Graciá - Food microbiology, 2019 - Elsevier
The epidemiology and transmission of Clostridioides difficile, particularly for community-
associated infections, are not completely understood. Although there have been no …