Advancing biomaterials of human origin for tissue engineering
FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …
devices and in the development of tissue engineering, which seeks to unlock the …
Mesenchymal stem/stromal cell secretome for lung regeneration: The long way through “pharmaceuticalization” for the best formulation
Pulmonary acute and chronic diseases, such as chronic obstructive pulmonary disease,
pulmonary fibrosis and pulmonary hypertension, are considered to be major health issues …
pulmonary fibrosis and pulmonary hypertension, are considered to be major health issues …
Perfusion decellularization of whole organs
The native extracellular matrix (ECM) outlines the architecture of organs and tissues. It
provides a unique niche of composition and form, which serves as a foundational scaffold …
provides a unique niche of composition and form, which serves as a foundational scaffold …
Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering
Approximately 285 million people worldwide suffer from diabetes, with insulin
supplementation as the most common treatment measure. Regenerative medicine …
supplementation as the most common treatment measure. Regenerative medicine …
Perfusion decellularization of human and porcine lungs: bringing the matrix to clinical scale
Background Organ engineering is a theoretical alternative to allotransplantation for end-
stage organ failure. Whole-organ scaffolds can be created by detergent perfusion via the …
stage organ failure. Whole-organ scaffolds can be created by detergent perfusion via the …
[HTML][HTML] Optimization and critical evaluation of decellularization strategies to develop renal extracellular matrix scaffolds as biological templates for organ engineering …
M Caralt, JS Uzarski, S Iacob, KP Obergfell… - American journal of …, 2015 - Elsevier
The ability to generate patient-specific cells through induced pluripotent stem cell (iPSC)
technology has encouraged development of three-dimensional extracellular matrix (ECM) …
technology has encouraged development of three-dimensional extracellular matrix (ECM) …
Assembly and function of a bioengineered human liver for transplantation generated solely from induced pluripotent stem cells
K Takeishi, AC de l'Hortet, Y Wang, K Handa… - Cell reports, 2020 - cell.com
The availability of an autologous transplantable auxiliary liver would dramatically affect the
treatment of liver disease. Assembly and function in vivo of a bioengineered human liver …
treatment of liver disease. Assembly and function in vivo of a bioengineered human liver …
[HTML][HTML] Decellularized matrices for cardiovascular tissue engineering
F Moroni, T Mirabella - American journal of stem cells, 2014 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is one of the leading causes of death in the Western world.
The replacement of damaged vessels and valves has been practiced since the 1950's …
The replacement of damaged vessels and valves has been practiced since the 1950's …
The human pancreas as a source of protolerogenic extracellular matrix scaffold for a new-generation bioartificial endocrine pancreas
Objectives: Our study aims at producing acellular extracellular matrix scaffolds from the
human pancreas (hpaECMs) as a first critical step toward the production of a new …
human pancreas (hpaECMs) as a first critical step toward the production of a new …
Bioengineered transplantable porcine livers with re-endothelialized vasculature
IK Ko, L Peng, A Peloso, CJ Smith, A Dhal, DB Deegan… - Biomaterials, 2015 - Elsevier
Donor shortage remains a continued challenge in liver transplantation. Recent advances in
tissue engineering have provided the possibility of creating functional liver tissues as an …
tissue engineering have provided the possibility of creating functional liver tissues as an …