Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010

MS Anglesio, MS Carey, M Köbel, H MacKay… - Gynecologic …, 2011 - Elsevier
OBJECTIVES: Recent literature has highlighted histological types of ovarian carcinoma as
distinct diseases, each with unique clinical and molecular features. Historically, the …

Clear cell carcinoma of the ovary: a review of the literature

MG Del Carmen, M Birrer, JO Schorge - Gynecologic oncology, 2012 - Elsevier
OBJECTIVE: Different histologic types of epithelial ovarian cancer may represent different
diseases with unique clinical and molecular characteristics. Clear cell carcinoma (CCC) of …

Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy

H Ikeda, H Kakeya - The Journal of Antibiotics, 2021 - nature.com
Tumor cells are often exposed to hypoxia because of the lower oxygen supply deep inside
the tumor tissues. However, tumor cells survive in these severe conditions by adapting to …

Randomized phase III trial of irinotecan plus cisplatin compared with paclitaxel plus carboplatin as first-line chemotherapy for ovarian clear cell carcinoma: JGOG3017 …

T Sugiyama, A Okamoto, T Enomoto… - Journal of clinical …, 2016 - ascopubs.org
Purpose Clear cell carcinoma (CCC) is a rare histologic subtype that demonstrates poor
outcomes in epithelial ovarian cancer. The Japanese Gynecologic Oncology Group …

Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

V Coothankandaswamy, S Cao, Y Xu… - British journal of …, 2016 - Wiley Online Library
Background and Purpose Pancreatic cancer is a solid tumour that is often fatal. Hence, there
is an urgent need to identify new drug targets for this disease. Highly proliferating cancer …

Clear cell carcinoma of the ovary: molecular insights and future therapeutic perspectives

S Mabuchi, T Sugiyama… - Journal of gynecologic …, 2016 - synapse.koreamed.org
Clear cell carcinoma (CCC) of the ovary is known to show poorer sensitivity to
chemotherapeutic agents and to be associated with a worse prognosis than the more …

Potential therapeutic effects of mTOR inhibition in atherosclerosis

A Kurdi, GRY De Meyer… - British journal of clinical …, 2016 - Wiley Online Library
Despite significant improvement in the management of atherosclerosis, this slowly
progressing disease continues to affect countless patients around the world. Recently, the …

The potential role of HIF on tumour progression and dissemination

S Unwith, H Zhao, L Hennah… - International journal of …, 2015 - Wiley Online Library
Cancer is the second cause of mortality worldwide, primarily owing to failure to cure
metastatic disease. The need to target the metastatic process to reduce mortality is clear and …

Core–shell structured 5-FU@ ZIF-90@ ZnO as a biodegradable nanoplatform for synergistic cancer therapy

X Xiao, S Liang, Y Zhao, D Huang, B Xing, Z Cheng… - Nanoscale, 2020 - pubs.rsc.org
High treatment efficiency and low drug toxicity are two key factors in tumor therapy. The
development of multifunctional drug carrier systems is of great significance for the diagnosis …

Morphologic spectrum of immunohistochemically characterized clear cell carcinoma of the ovary: a study of 155 cases

D DeLair, E Oliva, M Köbel, A Macias… - The American journal …, 2011 - journals.lww.com
Establishing a diagnosis of ovarian clear cell carcinoma (O-CCC) can be subject to
significant interobserver variation. Accurately diagnosing this tumor is important because of …