DNA methylation markers in obesity, metabolic syndrome, and weight loss

M Samblas, FI Milagro, A Martínez - Epigenetics, 2019 - Taylor & Francis
The fact that not all individuals exposed to the same environmental risk factors develop
obesity supports the hypothesis of the existence of underlying genetic and epigenetic …

The FoxO–autophagy axis in health and disease

Z Cheng - Trends in Endocrinology & Metabolism, 2019 - cell.com
Autophagy controls cellular remodeling and quality control. Dysregulated autophagy has
been implicated in several human diseases including obesity, diabetes, cardiovascular …

Deciphering the tRNA-derived small RNAs: origin, development, and future

B Liu, J Cao, X Wang, C Guo, Y Liu, T Wang - Cell Death & Disease, 2021 - nature.com
Transfer RNA (tRNA)-derived small RNAs (tsRNAs), a novel category of small noncoding
RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the …

Insight into polyphenol and gut microbiota crosstalk: are their metabolites the key to understand protective effects against metabolic disorders?

M Koudoufio, Y Desjardins, F Feldman, S Spahis… - Antioxidants, 2020 - mdpi.com
Lifestyle factors, especially diet and nutrition, are currently regarded as essential avenues to
decrease modern-day cardiometabolic disorders (CMD), including obesity, metabolic …

Linking lipid metabolism to chromatin regulation in aging

K Papsdorf, A Brunet - Trends in cell biology, 2019 - cell.com
The lifespan of an organism is strongly influenced by environmental factors (including diet)
and by internal factors (notably reproductive status). Lipid metabolism is critical for …

Exercise and the control of muscle mass in human

M Francaux, L Deldicque - Pflügers Archiv-European Journal of Physiology, 2019 - Springer
During the course of life, muscle mass undergoes many changes in terms of quantity and
quality. Skeletal muscle is a dynamic tissue able to hypertrophy or atrophy according to …

Maternal obesity, maternal overnutrition and fetal programming: effects of epigenetic mechanisms on the development of metabolic disorders

E Şanlı, S Kabaran - Current genomics, 2019 - ingentaconnect.com
Background: Maternal obesity and maternal overnutrition, can lead to epigenetic alterations
during pregnancy and these alterations can influence fetal and neonatal phenotype which …

Association of cardiovascular health through young adulthood with genome-wide DNA methylation patterns in midlife: the CARDIA study

Y Zheng, BT Joyce, SJ Hwang, J Ma, L Liu, NB Allen… - Circulation, 2022 - Am Heart Assoc
Background: Cardiovascular health (CVH) from young adulthood is strongly associated with
an individual's future risk of cardiovascular disease (CVD) and total mortality. Defining …

Developmental origins of type 2 diabetes: Focus on epigenetics

A Vaiserman, O Lushchak - Ageing Research Reviews, 2019 - Elsevier
Traditionally, genetics and lifestyle are considered as main determinants of aging-
associated pathological conditions. Accumulating evidence, however, suggests that risk of …

Anticancer effects of nutraceuticals in the Mediterranean diet: an epigenetic diet model

R Divella, A Daniele, E Savino… - Cancer Genomics & …, 2020 - cgp.iiarjournals.org
Epidemiological and clinical studies support the association between nutrition and
development or progression of different malignancies such as colon, breast, and prostate …