Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology

LGN de Almeida, H Thode, Y Eslambolchi… - Pharmacological …, 2022 - ASPET
The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Peptide-based supramolecular systems chemistry

F Sheehan, D Sementa, A Jain, M Kumar… - Chemical …, 2021 - ACS Publications
Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …

Self‐assembling peptide‐based hydrogels for wound tissue repair

T Guan, J Li, C Chen, Y Liu - Advanced Science, 2022 - Wiley Online Library
Wound healing is a long‐term, multistage biological process that includes hemostasis,
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …

Molecularly stimuli-responsive self-assembled peptide nanoparticles for targeted imaging and therapy

Y Zhou, Q Li, Y Wu, X Li, Y Zhou, Z Wang, H Liang… - ACS …, 2023 - ACS Publications
Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …

Size-tunable strategies for a tumor targeted drug delivery system

W Yu, R Liu, Y Zhou, H Gao - ACS central science, 2020 - ACS Publications
Nanoparticles have been widely used in tumor targeted drug delivery, while the antitumor
effects are not always satisfactory due to the limited penetration and retention. As we all …

(Macro) molecular self-assembly for hydrogel drug delivery

MJ Webber, ET Pashuck - Advanced drug delivery reviews, 2021 - Elsevier
Hydrogels prepared via self-assembly offer scalable and tunable platforms for drug delivery
applications. Molecular-scale self-assembly leverages an interplay of attractive and …

Systems chemistry of peptide-assemblies for biochemical transformations

A Chatterjee, A Reja, S Pal, D Das - Chemical Society Reviews, 2022 - pubs.rsc.org
During the billions of years of the evolutionary journey, primitive polymers, involved in proto
metabolic pathways with low catalytic activity, played critical roles in the emergence of …

Phagocyte-membrane-coated and laser-responsive nanoparticles control primary and metastatic cancer by inducing anti-tumor immunity

C Hu, T Lei, Y Wang, J Cao, X Yang, L Qin, R Liu… - Biomaterials, 2020 - Elsevier
To achieve safe and effective antitumor immunity, we constructed the M1-macrophage-
membrane-coated nanoparticles [(C/I) BP@ BA (D) &M1m] having laser-responsive, size …

Stimuli-responsive cyclodextrin-based supramolecular assemblies as drug carriers

Y Yuan, T Nie, Y Fang, X You, H Huang… - Journal of Materials …, 2022 - pubs.rsc.org
Cyclodextrins (CDs) are widely employed in biomedical applications because of their
unique structures. Various biomedical applications can be achieved in a spatiotemporally …

[HTML][HTML] Enzyme-responsive nanoparticles for anti-tumor drug delivery

M Li, G Zhao, WK Su, Q Shuai - Frontiers in chemistry, 2020 - frontiersin.org
The past few decades have seen great progress in the exploration of nanoparticles (NPs) as
novel tools for cancer treatments and diagnosis. Practical and reliable application of …