The molecular memory code and synaptic plasticity: A synthesis

SJ Gershman - Biosystems, 2023 - Elsevier
The most widely accepted view of memory in the brain holds that synapses are the storage
sites of memory, and that memories are formed through associative modification of …

Neurophysiological coding of space and time in the hippocampus, entorhinal cortex, and retrosplenial cortex

AS Alexander, JC Robinson… - Brain and …, 2020 - journals.sagepub.com
Neurophysiological recordings in behaving rodents demonstrate neuronal response
properties that may code space and time for episodic memory and goal-directed behaviour …

Time cells in the human hippocampus and entorhinal cortex support episodic memory

G Umbach, P Kantak, J Jacobs… - Proceedings of the …, 2020 - National Acad Sciences
The organization of temporal information is critical for the encoding and retrieval of episodic
memories. In the rodent hippocampus and entorhinal cortex, evidence accumulated over the …

Place cells may simply be memory cells: Memory compression leads to spatial tuning and history dependence

MK Benna, S Fusi - … of the National Academy of Sciences, 2021 - National Acad Sciences
The observation of place cells has suggested that the hippocampus plays a special role in
encoding spatial information. However, place cell responses are modulated by several …

A neural network model of when to retrieve and encode episodic memories

Q Lu, U Hasson, KA Norman - elife, 2022 - elifesciences.org
Recent human behavioral and neuroimaging results suggest that people are selective in
when they encode and retrieve episodic memories. To explain these findings, we trained a …

[HTML][HTML] Neural sequences as an optimal dynamical regime for the readout of time

S Zhou, SC Masmanidis, DV Buonomano - Neuron, 2020 - cell.com
Converging evidence suggests that the brain encodes time through dynamically changing
patterns of neural activity, including neural sequences, ramping activity, and complex …

A temporal record of the past with a spectrum of time constants in the monkey entorhinal cortex

IM Bright, MLR Meister, NA Cruzado… - Proceedings of the …, 2020 - National Acad Sciences
Episodic memory is believed to be intimately related to our experience of the passage of
time. Indeed, neurons in the hippocampus and other brain regions critical to episodic …

Keeping time and rhythm by internal simulation of sensory stimuli and behavioral actions

V de Lafuente, M Jazayeri, H Merchant… - Science …, 2024 - science.org
Effective behavior often requires synchronizing our actions with changes in the environment.
Rhythmic changes in the environment are easy to predict, and we can readily time our …

[HTML][HTML] The generation of time in the hippocampal memory system

ET Rolls, P Mills - Cell reports, 2019 - cell.com
We propose that ramping time cells in the lateral entorhinal cortex can be produced by
synaptic adaptation and demonstrate this in an integrate-and-fire attractor network model …

Internally generated time in the rodent hippocampus is logarithmically compressed

R Cao, JH Bladon, SJ Charczynski, ME Hasselmo… - Elife, 2022 - elifesciences.org
Abstract The Weber-Fechner law proposes that our perceived sensory input increases with
physical input on a logarithmic scale. Hippocampal 'time cells' carry a record of recent …