Chemical synthesis of oligosaccharides and their application in new drug research

Z Lv, H Liu, H Hao, FU Rahman, Y Zhang - European Journal of Medicinal …, 2023 - Elsevier
Oligosaccharides are the ubiquitous molecules of life. In order to translate human
bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and …

Stereoselective Synthesis of O-Glycosides with Borate Acceptors

X Zhao, Z Zhang, J Xu, N Wang… - The Journal of Organic …, 2023 - ACS Publications
Borate esters have been applied widely as coupling partners in organic synthesis. However,
the direct utilization of borate acceptors in O-glycosylation with glycal donors remains …

Visible-light-promoted desulfurization to synthesize deoxyglycosides

T Luo, YF Guo, TT Xu, H Dong - The Journal of Organic Chemistry, 2023 - ACS Publications
In this study, we have successfully applied a visible-light-promoted desulfurization method to
the synthesis of deoxysugars, especially 1-deoxyglycose, 2, 4-deoxyglycosides, and 2 …

Influence of C-4 Axial/Equatorial Configuration and Neighboring Group/Remote Group Participation (NGP/RGP) Driven Conformational Evidence in Chemoselective …

N Kumar, A Gurawa, A Yadav, S Kashyap - Organic Letters, 2024 - ACS Publications
We herein reveal the possibility of the C-4 neighboring group/remote group participation
(NGP/RGP) facilitating the stabilization of the anomeric center via dioxolenium intermediates …

Anion‐Bridged Dual Hydrogen Bond Enabled Concerted Addition of Phenol to Glycal

Q Jiao, Z Guo, M Zheng, W Lin, Y Liao… - Advanced …, 2024 - Wiley Online Library
A noncovalent organocatalytic concerted addition of phenol to glycal is developed for the
stereoselective and regioselective construction of biologically important phenolic 2 …

Development of α-Selective Glycosylation with l-Oleandral and Its Application to the Total Synthesis of Oleandrin

N Carney, N Perry, J Garabedian, P Nagorny - Organic letters, 2023 - ACS Publications
This letter describes the development of an α-selective glycosylation using l-oleandrose, a 2-
deoxysugar that is frequently found in natural products, and its application to the total …

Shape-controlled synthesis of varied bismuth nanostructures and their size-dependent photocatalytic removal of organic dyes under visible light irradiation

D Ma, S Pan, M Tan, G He, J Zhao - Optical Materials, 2023 - Elsevier
The catalytic activity of photocatalyst is strongly dependent on the phase structures, grain
size and particle morphology of the catalyst. In this paper, the controlled synthesis of bismuth …

Reagent-controlled chemo/stereoselective glycosylation of ʟ-fucal to access rare deoxysugars

N Kumar, M Yadav, S Kashyap - Carbohydrate Research, 2024 - Elsevier
Dideoxy sugars constitute an important class of anticancer antibiotics natural products and
serve as essential medicinal tools for carbohydrate-based drug discovery and vaccine …

Electrochemical Carbon-Ferrier Rearrangement Using a Microflow Reactor and Machine Learning-Assisted Exploration of Suitable Conditions

E Sato, G Tachiwaki, M Fujii, K Mitsudo… - … Process Research & …, 2023 - ACS Publications
The use of a flow reactor in electrolysis enables efficient and scalable synthesis, which is
normally difficult to accomplish by batch reactors. We achieved electrochemical carbon …

Stereoselective Synthesis of 2-Deoxythiosugars from Glycals

X You, Y Cai, C Xiao, L Ma, Y Wei, T Xie, L Chen… - Molecules, 2022 - mdpi.com
2-deoxythiosugars are more stable than 2-deoxysugars occurring broadly in bioactive
natural products and pharmaceutical agents. An effective and direct methodology to …