Biophysical cues play a key role in directing the lineage commitment of mesenchymal stem
cells or multipotent stromal cells (MSC s), but the mechanotransductive mechanisms at play …

Silks are naturally occurring polymers that have been used clinically as sutures for centuries.
When naturally extruded from insects or worms, silk is composed of a filament core protein …

Tissue engineering (TE) is a multidisciplinary field that aims at the in vitro engineering of
tissues and organs by integrating science and technology of cells, materials and …

Recently, research is undergoing a drastic change in the application of the animal model as
a unique investigation strategy, considering an alternative approach for the development of …

Silk fibroin sol− gel transitions were studied by monitoring the process under various
physicochemical conditions with optical spectroscopy at 550 nm. The secondary structural …

The silk fibroin (SF) prepared by Bombyx mori silkworms is one of the mainly abundant
natural fiber and can be obtained simply and economically. SF as bio-material has superior …

Adult cartilage tissue has limited self-repair capacity, especially in the case of severe
damages caused by developmental abnormalities, trauma, or aging-related degeneration …

The pharmaceutical utility of silk fibroin (SF) materials for drug delivery was investigated. SF
films were prepared from aqueous solutions of the fibroin protein polymer and crystallinity …

Mechanical cell stretching may be an attractive strategy for the tissue engineering of
mechanically functional tissues. It has been demonstrated that cell growth and differentiation …

Scarring and tissue fibrosis represent a significant source of morbidity in the United States.
Despite considerable research focused on elucidating the mechanisms underlying …