[HTML][HTML] Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

[HTML][HTML] The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Diet–microbiota interactions and personalized nutrition

AA Kolodziejczyk, D Zheng, E Elinav - Nature Reviews Microbiology, 2019 - nature.com
Conceptual scientific and medical advances have led to a recent realization that there may
be no single, one-size-fits-all diet and that differential human responses to dietary inputs …

[HTML][HTML] Short chain fatty acids (SCFAs)-mediated gut epithelial and immune regulation and its relevance for inflammatory bowel diseases

D Parada Venegas, MK De la Fuente… - Frontiers in …, 2019 - frontiersin.org
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel
Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial …

High levels of butyrate and propionate in early life are associated with protection against atopy

C Roduit, R Frei, R Ferstl, S Loeliger, P Westermann… - Allergy, 2019 - Wiley Online Library
Background Dietary changes are suggested to play a role in the increasing prevalence of
allergic diseases and asthma. Short‐chain fatty acids (SCFA s) are metabolites present in …

Short chain fatty acids as potential therapeutic agents in human gastrointestinal and inflammatory disorders

PA Gill, MC Van Zelm, JG Muir… - Alimentary …, 2018 - Wiley Online Library
Background Butyrate, propionate and acetate are short chain fatty acids (SCFA), important
for maintaining a healthy colon and are considered as protective in colorectal …

Microbiota and metabolic diseases

A Pascale, N Marchesi, C Marelli, A Coppola, L Luzi… - Endocrine, 2018 - Springer
The microbiota is a complex ecosystem of microorganisms consisting of bacteria, viruses,
protozoa, and fungi, living in different districts of the human body, such as the gastro-enteric …

Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use

T van Deuren, EE Blaak, EE Canfora - Obesity Reviews, 2022 - Wiley Online Library
Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

The neuropharmacology of butyrate: the bread and butter of the microbiota-gut-brain axis?

RM Stilling, M Van De Wouw, G Clarke… - Neurochemistry …, 2016 - Elsevier
Several lines of evidence suggest that brain function and behaviour are influenced by
microbial metabolites. Key products of the microbiota are short-chain fatty acids (SCFAs) …

The gut microbiota, bacterial metabolites and colorectal cancer

P Louis, GL Hold, HJ Flint - Nature reviews microbiology, 2014 - nature.com
Accumulating evidence suggests that the human intestinal microbiota contributes to the
aetiology of colorectal cancer (CRC), not only via the pro-carcinogenic activities of specific …